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Bacteriorhodopsin — the movie

For 30 years and more, the mechanism of a microbial proton pump has been subject to increasingly sophisticated analysis. The full picture of how the pump operates is now emerging.

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Figure 1: Molecular mechanism of proton (H+) pumping in bacteriorhodopsin. Retinal is bound in the space between the seven membrane-spanning helices (A to G) by a lysine in helix G.

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Correspondence to Werner Kühlbrandt.

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Kühlbrandt, W. Bacteriorhodopsin — the movie. Nature 406, 569–570 (2000). https://doi.org/10.1038/35020654

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