Brief Communication | Published:

Nutrition

Antioxidant activity of fresh apples

Nature volume 405, pages 903904 (22 June 2000) | Download Citation

Subjects

Abstract

Vitamin C is used as a dietary supplement because of its antioxidant activity, although a high dose (500 mg) may act as a pro-oxidant in the body1,2. Here we show that 100 g of fresh apples has an antioxidant activity equivalent to 1,500 mg of vitamin C, and that whole-apple extracts inhibit the growth of colon- and liver- cancer cells in vitro in a dose-dependent manner. Our results indicate that natural antioxidants from fresh fruit could be more effective than a dietary supplement.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nature 392, 559 ( 1998).

  2. 2.

    et al. J. Nutr. 126, 1213S– 1220S (1996).

  3. 3.

    & Am. J. Enol. Viticult. 16, 144–158 (1965).

  4. 4.

    , & Food Chem. 64, 555– 559 (1999).

  5. 5.

    , & J. Agric. Food Chem. 38, 945– 948 (1990).

  6. 6.

    , , , & Free Rad. Biol. Med. 24, 480 –493 (1998).

  7. 7.

    USDA Nutrient Database for Standard Reference ( 1998).

  8. 8.

    , & J. Agric. Food Chem. 44, 701– 705 (1998).

  9. 9.

    J. Int. Fed. Clin. Chem. 4, 58–63 (1992).

  10. 10.

    , , & Cancer Commun. 3, 207–212 (1991).

Download references

Author information

Affiliations

  1. Department of Food Science, 108 Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA

    • Marian V. Eberhardt
    • , Chang Yong Lee
    •  & Rui Hai Liu

Authors

  1. Search for Marian V. Eberhardt in:

  2. Search for Chang Yong Lee in:

  3. Search for Rui Hai Liu in:

Corresponding author

Correspondence to Rui Hai Liu.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/35016151

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.