Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Adhesion receptors of the immune system

Nature volume 346, pages 425–434 (1990)Cite this article

Abstract

The adhesive interactions of cells with other cells and with the extracellular matrix are crucial to all developmental processes, but have a central role in the functions of the immune system throughout life. Three families of cell-surface molecules regulate the migration of lymphocytes and the interactions of activated cells during immune responses.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

Buy

All prices are NET prices.

References

  1. Sperry, R. W. Proc. natn. Acad. Sci. U.S.A. 50, 703–710 (1963).

    CAS  ADS  Google Scholar 

  2. Ruoslahti, E. & Pierschbacher, M. D. Science 238, 491–497 (1987).

    CAS  PubMed  ADS  Google Scholar 

  3. Trinkaus, J. P. Cells into Organs: The Forces that Shape the Embryo (Prentice-Hall, Englewood Cliffs, 1984).

    Google Scholar 

  4. Parrott, D. M. V. & Wilkinson, P. C. Prog. Allergy 28, 193–284 (1981).

    CAS  PubMed  Google Scholar 

  5. Bierer, B. E., Sleckman, B. P., Ratnofsky, S. E. & Burakoff, S. J. A. Rev. Immun. 7, 579–599 (1989).

    CAS  Google Scholar 

  6. Swain, S. L. Immunol. Rev. 74, 129–142 (1983).

    CAS  PubMed  Google Scholar 

  7. Spits, H. et al. Science 232, 403–405 (1986).

    CAS  PubMed  ADS  Google Scholar 

  8. Shaw, S. et al. Nature 323, 262–265 (1986).

    CAS  PubMed  ADS  Google Scholar 

  9. Doyle, C. & Strominger, J. L. Nature 330, 256–259 (1987).

    Article  CAS  ADS  PubMed  Google Scholar 

  10. Norment, A. M., Salter, R. D., Parham, P., Engelhard, V. H. & Littman, D. R. Nature 336, 79–81 (1988).

    Article  CAS  ADS  PubMed  Google Scholar 

  11. Janeway, C. A. Nature 335, 208–210 (1988).

    ADS  PubMed  Google Scholar 

  12. von Boehmer, H. A. Rev. Immun. 6, 309–326 (1988).

    CAS  Google Scholar 

  13. Parnes, J. R. Adv. Immun. 44, 265–311 (1989).

    CAS  PubMed  Google Scholar 

  14. Kupfer, A. & Singer, S. J. A. Rev. Immun. 7, 309–337 (1989).

    CAS  Google Scholar 

  15. Salter, R. D. et al. Nature 345, 41–46 (1990).

    CAS  PubMed  ADS  Google Scholar 

  16. Potter, T. A., Rajan, T. V., Dick, R. F. & Bluestone, J. A. Nature 337, 73–75 (1989).

    CAS  ADS  PubMed  Google Scholar 

  17. Bjorkman, P. J. et al. Nature 329, 512–518 (1987).

    Article  CAS  ADS  PubMed  Google Scholar 

  18. Turner, J. M. et al. Cell 60, 755–765 (1990).

    CAS  PubMed  Google Scholar 

  19. Springer, T. A., Dustin, M. L., Kishimoto, T. K. & Marlin, S. D. A. Rev. Immun. 5, 223–252 (1987).

    CAS  Google Scholar 

  20. Martz, E. Hum. Immun. 18, 3–37 (1987).

    CAS  PubMed  Google Scholar 

  21. Kishimoto, T. K. et al. Adv. Immun. 46, 149–182 (1989).

    CAS  PubMed  Google Scholar 

  22. Shaw, S. & Luce, G. E. G. J. Immun. 139, 1037–1045 (1987).

    CAS  PubMed  Google Scholar 

  23. Dustin, M. L. & Springer, T. A. Nature 341, 619–624 (1989).

    CAS  PubMed  ADS  Google Scholar 

  24. Butcher, E. C. Curr. Topics Microbiol. Immun. 128, 85–122 (1986).

    CAS  Google Scholar 

  25. Kishimoto, T. K., O'Connor, K., Lee, A., Roberts, T. M. & Springer, T. A. Cell 48, 681–690 (1987).

    CAS  PubMed  Google Scholar 

  26. Larson, R. S., Corbi, A. L., Berman, L. & Springer, T. A. J. Cell Biol. 108, 703–712 (1989).

    CAS  PubMed  Google Scholar 

  27. Simmons, D., Makgoba, M. W. & Seed, B. Nature 331, 624–627 (1988).

    CAS  PubMed  ADS  Google Scholar 

  28. Staunton, D. E., Marlin, S. D., Stratowa, C., Dustin, M. L. & Springer, T. A. Cell 52, 925–933 (1988).

    CAS  PubMed  Google Scholar 

  29. Staunton, D. E., Dustin, M. L. & Springer, T. A. Nature 339, 61–64 (1989).

    CAS  PubMed  ADS  Google Scholar 

  30. Selvaraj, P. et al. Nature 326, 400–403 (1987).

    CAS  PubMed  ADS  Google Scholar 

  31. Dustin, M. L., Sanders, M. E., Shaw, S. & Springer, T. A. J. exp. Med. 165, 677–692 (1987).

    CAS  PubMed  Google Scholar 

  32. Haynes, B. F. Adv. Immun. 36, 87–142 (1984).

    CAS  PubMed  Google Scholar 

  33. Wigzell, H. & Hayry, P. Curr. Topics Microbiol. Immun. 67, 1–42 (1974).

    CAS  Google Scholar 

  34. Bell, G. I., Dembo, M. & Bongrand, P. Biophys. J. 45, 1051–1064 (1984).

    CAS  PubMed  PubMed Central  Google Scholar 

  35. Plunkett, M. L., Sanders, M. E., Selvaraj, P., Dustin, M. L. & Springer, T. A. J. exp. Med. 165, 664–676 (1987).

    CAS  PubMed  Google Scholar 

  36. Bentwich, Z., Douglas, S. D., Siegal, F. P. & Kunkel, H. G. Clin. Immun. Immunopath. 1, 511–522 (1973).

    CAS  PubMed  Google Scholar 

  37. Despont, J. P., Abel, C. A. & Grey, H. M. Cell Immun. 17, 487–494 (1975).

    CAS  Google Scholar 

  38. Shortman, K., von Boehmer, H., Lipp, J. & Hopper, K. Transplantn Rev. 25, 163–210 (1975).

    CAS  Google Scholar 

  39. Butcher, E. C. et al. J. Immun. 129, 2698–2707 (1982).

    CAS  PubMed  Google Scholar 

  40. Rutishauser, U., Acheson, A., Hall, A. K., Mann, D. M. & Sunshine, J. Science 240, 53–57 (1988).

    CAS  PubMed  ADS  Google Scholar 

  41. Springer, T. A. A. Rev. Cell Biol. 6, 359–402 (1990).

    CAS  Google Scholar 

  42. Dustin, M. L., Olive, D. & Springer, T. A. J. exp. Med 169, 503–517 (1989).

    CAS  PubMed  Google Scholar 

  43. Sayre, P. H., Hussey, R. E., Chang, H. C., Ciardelli, T. L. & Reinherz, E. L. J. exp. Med. 169, 995–1009 (1989).

    CAS  PubMed  Google Scholar 

  44. Tiefenthaler, G., Hünig, T., Dustin, M. L., Springer, T. A. & Meuer, S. C. Eur. J. Immun. 17, 1847–1850 (1987).

    CAS  Google Scholar 

  45. Bierer, B. E., Peterson, A., Gorga, J. C., Herrmann, S. H. & Burakoff, S. J. J. exp. Med. 168, 1145–1156 (1988).

    CAS  PubMed  Google Scholar 

  46. Moingeon, P., Chang, H. C., Wallner, B. P., Stebbins, C., Frey, A. Z. & Reinherz, E. L. Nature 339, 312–314 (1989).

    CAS  PubMed  ADS  Google Scholar 

  47. He, Q., Beyers, A. D., Barclay, A. N. & Williams, A. F. Cell 54, 979–984 (1988).

    CAS  PubMed  Google Scholar 

  48. Seed, B. Nature 329, 840–842 (1987).

    CAS  PubMed  ADS  Google Scholar 

  49. Dustin, M. L., Selvaraj, P., Mattaliano, R. J. & Springer, T. A. Nature 329, 846–848 (1987).

    CAS  PubMed  ADS  Google Scholar 

  50. Wallner, B. P. et al. J. exp. Med. 166, 923–934 (1987).

    CAS  PubMed  Google Scholar 

  51. Hollander, N., Selvaraj, P. & Springer, T. A. J. Immun. 141, 4283–4290 (1988).

    CAS  PubMed  Google Scholar 

  52. Cunningham, B. A. et al. Science 236, 799–806 (1987).

    CAS  PubMed  ADS  Google Scholar 

  53. Dustin, M. L., Staunton, D. E. & Springer, T. A. Immun. Today 9, 213–215 (1988).

    CAS  PubMed  Google Scholar 

  54. Rothlein, R. & Springer, T. A. J. exp. Med. 163, 1132–1149 (1986).

    CAS  PubMed  Google Scholar 

  55. Rothlein, R., Dustin, M. L., Marlin, S. D. & Springer, T. A. J. Immun. 137, 1270–1274 (1986).

    CAS  PubMed  Google Scholar 

  56. Dustin, M. L., Rothlein, R., Bhan, A. K., Dinarello, C. A. & Springer, T. A. J. Immun. 137, 245–254 (1986).

    CAS  PubMed  Google Scholar 

  57. Makgoba, M. W. et al. Eur. J. Immun. 18, 637–640 (1988).

    CAS  Google Scholar 

  58. Altmann, D. M., Hogg, N., Trowsdale, J. & Wilkinson, D. Nature 338, 512–514 (1989).

    CAS  PubMed  ADS  Google Scholar 

  59. Dustin, M. L. & Springer, T. A. J. Cell Biol. 107, 321–331 (1988).

    CAS  PubMed  Google Scholar 

  60. Wantzin, G. L. et al. J. Am. Acad. Dermat. 20, 782–790 (1989).

    Google Scholar 

  61. Munro, J. M., Pober, J. S. & Cotran, R. S. Am. J. Path. 135, 121–133 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  62. Reichner, J. S., Whiteheart, S. W. & Hart, G. W. J. biol. Chem. 263, 16316–16326 (1988).

    CAS  PubMed  Google Scholar 

  63. Poenie, M., Tsien, R. Y. & Schmitt-Verhulst, A. EMBO J. 6, 2223–2232 (1987).

    CAS  PubMed  PubMed Central  Google Scholar 

  64. Anderson, D. C. & Springer, T. A. A. Rev. Med. 38, 175–194 (1987).

    CAS  Google Scholar 

  65. Hynes, R. O. Cell 48, 549–554 (1987).

    CAS  PubMed  Google Scholar 

  66. Ruoslahti, E. & Pierschbacher, M. D. Cell 44, 517–518 (1986).

    CAS  PubMed  Google Scholar 

  67. Hemler, M. E. A. Rev. Immun. 8, 365–400 (1990).

    CAS  Google Scholar 

  68. Wayner, E. A., Garciz-Pardo, A., Humphries, M. J., MacDonald, J. A. & Carter, W. G. J. Cell Biol. 109, 1321–1330 (1989).

    CAS  PubMed  Google Scholar 

  69. Guan, J. L. & Hynes, R. O. Cell 60, 53–61 (1990).

    CAS  PubMed  Google Scholar 

  70. Osborn, L. et al. Cell 59, 1203–1211 (1989).

    CAS  PubMed  Google Scholar 

  71. Elices, M. J. et al. Cell 60, 577–584 (1990).

    CAS  PubMed  Google Scholar 

  72. Rice, G. E., Munro, J. M. & Bevilacqua, M. P. J. exp. Med. 171, 1369–1374 (1990).

    CAS  PubMed  Google Scholar 

  73. Haskard, D., Cavender, D., Beatty, P., Springer, T. & Ziff, M. J. Immun. 137, 2901–2906 (1986).

    CAS  PubMed  Google Scholar 

  74. Takada, Y., Elices, M. J., Crouse, C. & Hemler, M. E. EMBO J. 8, 1361–1368 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  75. Bednarczyk, J. L. & Mclntyre, B. W. J. Immun. 144, 777–784 (1990).

    CAS  PubMed  Google Scholar 

  76. Holzmann, B., Mclntyre, B. W. & Weissman, I. L. Cell 56, 37–46 (1989).

    CAS  PubMed  Google Scholar 

  77. Kajiji, S., Tamura, R. N. & Quaranta, V. EMBO J. 8, 673–680 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  78. Sonnenberg, A., Hogervorst, F., Osterop, A. & Veltman, F. E. M. J. biol. Chem. 263, 14030–14038 (1988).

    CAS  PubMed  Google Scholar 

  79. Hemler, M. E., Crouse, C. & Sonnenberg, A. J. biol. Chem. 264, 6529–6535 (1989).

    CAS  PubMed  Google Scholar 

  80. Cheresh, D. A., Smith, J. W., Cooper, H. M. & Quaranta, V. Cell 57, 59–69 (1989).

    CAS  PubMed  Google Scholar 

  81. Freed, E., Gailit, J., van der Geer, P., Rouslahti, E. & Hunter, T. EMBO J. 8, 2955–2965 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  82. Holzmann, B. & Weissman, I. L. EMBO J. 8, 1735–1741 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  83. D'Souza, S. E., Ginsberg, M. H., Burke, T. A., Lam, S. C.-T. & Plow, E. F. Science 242, 91–93 (1988).

    CAS  PubMed  ADS  Google Scholar 

  84. Wardlaw, A. J., Hibbs, M. L., Stacker, S. A. & Springer, T. A. J. exp. Med. 172, 335–345 (1990).

    CAS  PubMed  Google Scholar 

  85. Corbi, A. L., Miller, L. J., O'Connor, K., Larson, R. S. & Springer, T. A. EMBO J. 6, 4023–4028 (1987).

    CAS  PubMed  PubMed Central  Google Scholar 

  86. D'Souza, S. E., Ginsberg, M. H., Burke, T. A. & Plow, E. F. J. biol. Chem. 265, 3440–3446 (1990).

    CAS  PubMed  Google Scholar 

  87. Burridge, K., Fath, K., Kelly, T., Nuckolls, G. & Turner, C. A. Rev. Cell Biol. 4, 487–525 (1988).

    CAS  Google Scholar 

  88. Horwitz, A., Duggan, K., Buck, C., Beckerle, M. C. & Burridge, K. Nature 320, 531–533 (1986).

    CAS  PubMed  ADS  Google Scholar 

  89. Kupfer, A. & Singer, S. J. J. exp. Med. 170, 1697–1713 (1989).

    CAS  PubMed  Google Scholar 

  90. van Noesel, C. et al. Nature 333, 850–855 (1988).

    CAS  PubMed  ADS  Google Scholar 

  91. Pircher, H. et al. Eur. J. Immun. 16, 172–181 (1986).

    CAS  Google Scholar 

  92. Shimizu, Y., Van Seventer, G. A., Horgan, K. J. & Shaw, S. Immunol. Rev. 114, 109–143 (1990).

    CAS  PubMed  Google Scholar 

  93. Matsuyama, T. et al. J. exp. Med. 170, 1133–1148 (1989).

    CAS  PubMed  Google Scholar 

  94. Shimizu, Y., Van Seventer, G. A., Horgan, K. J. & Shaw, S. Nature 345, 250–253 (1990).

    CAS  PubMed  ADS  Google Scholar 

  95. Plow, E. F. & Ginsberg, M. H. Prog. Hemostasis & Thromb. 9, 117–156 (1989).

    CAS  Google Scholar 

  96. Keizer, G. D., Visser, W., Vleim, M. & Figdor, C. G. J. Immun. 140, 1393–1400 (1988).

    CAS  PubMed  Google Scholar 

  97. Wright, S. D. & Meyer, B. C. J. Immun. 136, 1759–1764 (1986).

    CAS  PubMed  Google Scholar 

  98. Buyon, J. P. et al. J. Immun. 140, 3156–3160 (1988).

    CAS  PubMed  Google Scholar 

  99. Lo, S. K., Detmers, P. A., Levin, S. M. & Wright, S. D. J. exp. Med. 169, 1779–1793 (1989).

    CAS  PubMed  Google Scholar 

  100. Hibbs, M. L. et al. J. clin. Invest. 85, 674–681 (1990).

    CAS  PubMed  PubMed Central  Google Scholar 

  101. Cerottini, J.-C. & MacDonald, H. R. A. Rev. Immun. 7, 77–89 (1989).

    CAS  Google Scholar 

  102. Sanders, M. E. et al. J. Immun. 140, 1401–1407 (1988).

    CAS  PubMed  Google Scholar 

  103. Janossy, G., Bofill, M., Rowe, D., Muir, J. & Beverley, P. C. Immunology 66, 517–525 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  104. Mackay, C. R., Marston, W. L. & Dudler, L. J. exp. Med. 171, 810–817 (1990).

    Google Scholar 

  105. Morimoto, C. et al. J. Immun. 134, 3762–3769 (1985).

    CAS  PubMed  Google Scholar 

  106. Tedder, T. F., Cooper, M. D. & Clement, L. T. J. Immun. 134, 2989–2994 (1985).

    CAS  PubMed  Google Scholar 

  107. Sanders, M. E., Makgoba, M. W., June, C. H., Young, H. A. & Shaw, S. Eur. J. Immun. 19, 803–808 (1989).

    CAS  Google Scholar 

  108. Yednock, T. A. & Rosen, S. D. Adv. Immun. 44, 313–378 (1989).

    CAS  PubMed  Google Scholar 

  109. Stoolman, L. M. Cell 56, 907–910 (1989).

    CAS  PubMed  Google Scholar 

  110. Tedder, T. F. et al. J. exp. Med. 170, 123–133 (1989).

    CAS  PubMed  Google Scholar 

  111. Tedder, T. F., Penta, A. C., Levine, H. B. & Freedman, A. S. J. Immun. 144, 532–540 (1990).

    CAS  PubMed  Google Scholar 

  112. Bevilacqua, M. P., Stengelin, S., Gimbrone, M. A. & Seed, B. Science 243, 1160–1165 (1989).

    CAS  ADS  PubMed  Google Scholar 

  113. Lasky, L. A. et al. Cell 56, 1045–1055 (1989).

    CAS  PubMed  Google Scholar 

  114. Siegelman, M. H., Van de Rijn, M. & Weissman, I. L. Science 243, 1165–1172 (1989).

    CAS  ADS  PubMed  Google Scholar 

  115. Johnston, G. I., Cook, R. G. & McEver, R. P. Cell 56, 1033–1044 (1989).

    CAS  PubMed  Google Scholar 

  116. Jutila, M. A., Rott, L., Berg, E. L. & Butcher, E. C. J. Immun. 143, 3318–3324 (1989).

    CAS  PubMed  Google Scholar 

  117. Kishimoto, T. K., Jutila, M. A., Berg, E. L. & Butcher, E. C. Science 245, 1238–1241 (1989).

    CAS  PubMed  ADS  Google Scholar 

  118. Luscinskas, F. W., Brock, A. F., Arnaout, M. A. & Gimbrone, M. A. J. Immun. 142, 2257–2263 (1989).

    CAS  PubMed  Google Scholar 

  119. Gimbrone, M. A. et al. Science 246, 1601–1603 (1989).

    CAS  PubMed  ADS  Google Scholar 

  120. Smith, C. W., Marlin, S. D., Rothlein, R., Toman, C. & Anderson, D. C. J. clin. Invest. 83, 2008–2017 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

  121. Lawrence, M. B., Smith, C. W., Eskin, S. G. & Mclntire, L. V. Blood 75, 227–237 (1990).

    CAS  PubMed  Google Scholar 

  122. Larsen, E. et al. Cell 59, 305–312 (1989).

    CAS  PubMed  Google Scholar 

  123. White, J. M. & Littman, D. R. Cell 56, 725–728 (1989).

    CAS  PubMed  Google Scholar 

  124. Sattentau, Q. J. & Weiss, R. A. Cell 52, 631–633 (1988).

    CAS  PubMed  Google Scholar 

  125. Linette, G. P., Hatzman, R. J., Ledbetter, J. A. & June, C. H. Science 241, 573–576 (1988).

    CAS  PubMed  ADS  Google Scholar 

  126. Hildreth, J. E. K. & Orentas, R. J. Science 244, 1075–1078 (1989).

    CAS  PubMed  ADS  Google Scholar 

  127. Landau, N. R., Warton, M. & Littman, D. R. Nature 334, 159–167 (1988).

    CAS  ADS  PubMed  Google Scholar 

  128. Peterson, A. & Seed, B. Cell 54, 65–72 (1988).

    CAS  PubMed  Google Scholar 

  129. Clayton, L. K., Sieh, M., Pious, D. A. & Reinherz, E. L. Nature 339, 548–551 (1989).

    CAS  PubMed  ADS  Google Scholar 

  130. Staunton, D. E., Dustin, M. L., Erickson, H. P. & Springer, T. A. Cell 61, 243–254 (1990).

    CAS  PubMed  Google Scholar 

  131. Verschueren, H. J. cell. Sci. 75, 279–301 (1985).

    CAS  PubMed  Google Scholar 

  132. Williams, A. F. & Barclay, A. N. in Immunochemistry (eds Weir, D. M., Herzenberg, L. A., Blackwell, C. & Herzenberg, L. A.) Ch. 22 (Blackwell, Oxford, 1986).

    Google Scholar 

  133. Ostergaard, H. L. et al. Proc. natn. Acad. Sci. U.S.A. 86, 8959–8963 (1989).

    CAS  ADS  Google Scholar 

  134. Lee, J., Gustafsson, M., Magnusson, K. E. & Jacobson, K. Science 247, 1229–1233 (1990).

    CAS  PubMed  ADS  Google Scholar 

  135. Sheetz, M. P., Turney, S., Qian, H. & Elson, E. L. Nature 340, 284–288 (1989).

    CAS  ADS  PubMed  Google Scholar 

  136. Williams, A. F. & Barclay, A. N. A. Rev. Immun. 6, 381–405 (1988).

    CAS  Google Scholar 

  137. Alzari, P. M., Lascombe, M.-B. & Poljak, R. J. A. Rev. Immun. 6, 555–580 (1988).

    CAS  Google Scholar 

  138. Harrelson, A. L. & Goodman, C. S. Science 242, 700–708 (1988).

    CAS  ADS  PubMed  Google Scholar 

  139. Becker, J. W., Erickson, H. P., Hoffman, S., Cunningham, B. A. & Edeiman, G. M. Proc. natn. Acad. Sci. U.S.A. 86, 1088–1092 (1989).

    CAS  ADS  Google Scholar 

  140. Davis, M. M. & Bjorkman, P. J. Nature 334, 395–402 (1988).

    CAS  PubMed  ADS  Google Scholar 

  141. Schulz, G. E. & Schirmer, R. H. Principles of Protein Structure (Springer-Verlag, New York, 1979).

    Google Scholar 

  142. Nermut, M.V., Green, N.M., Eason, P., Yamada, S.S. & Yamada, K.M. EMBO J. 7, 4093–4099 (1988).

    CAS  PubMed  PubMed Central  Google Scholar 

  143. Carrell, N. A., Fitzgerald, L. A., Steiner, B., Erickson, H. P. & Phillips, D. R. J. biol. Chem. 260, 1743–1749 (1985).

    CAS  PubMed  Google Scholar 

  144. Drickamer, K. J. biol. Chem. 263, 9557–9560 (1988).

    CAS  PubMed  Google Scholar 

  145. Dahlback, B., Smith, C. A. & Muller-Eberhard, H. J. Proc. natn. Acad. Sci. U.S.A. 80, 3461–3465 (1983).

    CAS  ADS  Google Scholar 

  146. Chung, L. P., Bentley, D. R. & Reid, K. B. Biochem. J. 230, 133–141 (1985).

    CAS  PubMed  PubMed Central  Google Scholar 

  147. Taylor, H. C. et al. J. cell. Biochem. 41, 71–90 (1989).

    CAS  PubMed  Google Scholar 

  148. Kileen, N., Barclay, A. N., Willis, A. C. & Williams, A. F. EMBO J. 6, 4029–4034 (1987).

    Google Scholar 

  149. Shelley, C. S. et al. Proc. natn. Acad. Sci. U.S.A. 86, 2819–2823 (1989).

    CAS  ADS  Google Scholar 

  150. Clemetson, K. J. Blood Cells 9, 319–329 (1983).

    CAS  PubMed  Google Scholar 

  151. Lopez, J. A. et al. Proc. natn. Acad. Sci. U.S.A. 84, 5615–5619 (1987).

    CAS  ADS  Google Scholar 

  152. Woollett, G. R., Williams, A. F. & Shotton, D. M. EMBO J. 4, 2827–2830 (1985).

    CAS  PubMed  PubMed Central  Google Scholar 

  153. Peterson, A. & Seed, B. Nature 329, 842–846 (1987).

    CAS  PubMed  ADS  Google Scholar 

  154. Kunicki, T. J. et al. J. Immun. 263, 4516–4519 (1988).

    CAS  Google Scholar 

  155. Wayner, E. A., Carter, W. G., Piotrowicz, R. S. & Kunick, T. J. J. Cell Biol. 107, 1881–1891 (1988).

    CAS  PubMed  Google Scholar 

  156. Languino, L. R. et al. J. Cell Biol. 109, 2455–2462 (1989).

    CAS  PubMed  Google Scholar 

  157. Takada, Y. & Hemler, M. E. J. Cell Biol. 109, 397–407 (1989).

    CAS  PubMed  Google Scholar 

  158. Sonnenberg, A., Modderman, P. W. & Hogervorst, F. Nature 336, 487–489 (1988).

    CAS  ADS  PubMed  Google Scholar 

  159. Savill, J., Dransfield, I., Hogg, N. & Haslett, C. Nature 343, 170–173 (1990).

    CAS  PubMed  ADS  Google Scholar 

  160. Krissansen, G. W. et al. J. biol. Chem. 265, 823–830 (1990).

    CAS  PubMed  Google Scholar 

  161. Vogel, B. E., Tarone, G., Giancotti, F. G., Gailit, J. & Ruoslahti, E. J. biol. Chem. 265, 5934–5937 (1990).

    CAS  PubMed  Google Scholar 

  162. Gilks, W. R., Spiegelhalter, D. J. & Cobbold, S. P. Leukocyte Typing Database III (Oxford University Press, 1988).

    Google Scholar 

  163. Selvaraj, P. et al. J. Immun. 139, 2690–2695 (1987).

    CAS  PubMed  Google Scholar 

  164. Rossmonn, M. G. J. biol. Chem. 264, 14587–14590 (1989).

    Google Scholar 

  165. Biberfeld, P. & Johansson, A. Expl Cell Res. 94, 79–87 (1975).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Department of Pathology, Harvard Medical School, and the Center for Blood Research, 800 Huntington Avenue, Boston, Massachusetts, 02115, USA

    Timothy A. Springer

Authors
  1. Timothy A. Springer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Springer, T. Adhesion receptors of the immune system. Nature 346, 425–434 (1990). https://doi.org/10.1038/346425a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/346425a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing