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Sex in flies: the splice of life

Nature volume 340, pages 521–524 (1989)Cite this article

Abstract

The discovery that the primary transcripts of many genes are processed to produce more than one kind of messenger RNA focuses attention on the control of RNA processing as a developmental regulatory mechanism. In the fruit-fly Drosophila melanogaster, differential splicing of a hierarchy of regulatory genes determines sex, and thus the molecular biology of sex determination in the fruit-fly may lead to insights into the mechanisms by which alternative splicing is regulated.

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Authors and Affiliations

  1. Department of Biological Sciences, Stanford University, Stanford, California, 94305, USA

    Bruce S. Baker

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  1. Bruce S. Baker
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Baker, B. Sex in flies: the splice of life. Nature 340, 521–524 (1989). https://doi.org/10.1038/340521a0

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