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Recombination occurs during telomere formation in yeast

Nature volume 337, pages 429–433 (1989)Cite this article

Abstract

Short stretches of cloned telomeric sequences are necessary and sufficient for telomere formation in yeast as long as the sequences are present in the same orientation as they are found in vivo. During telomere formation, DNA termini usually undergo RAD52-independent recombination with other DNA termini as would be predicted by models of recombination-mediated telomere replication.

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References

  1. Blackburn, E. H. Cell 37, 7–8 (1984).

    CAS  Article  Google Scholar 

  2. Allshire, R. C. et al. Nature 332, 656–659 (1988).

    ADS  CAS  Article  Google Scholar 

  3. Richards, E. J. & Ausubel, F. M. Cell 53, 127–136 (1988).

    CAS  Article  Google Scholar 

  4. Szostak, J. W. & Blackburn, E. H. Cell 29, 245–255 (1982).

    CAS  Article  Google Scholar 

  5. Dani, G. M. & Zakian, V. A. Proc. natn. Acad. Sci. U.S.A. 80, 3406–3410 (1983).

    ADS  CAS  Article  Google Scholar 

  6. Pluta, A. F., Dani, G. M., Spear, B. B. & Zakian, V. A. Proc. natn. Acad. Sci. U.S.A. 81, 1475–1479 (1984).

    ADS  CAS  Article  Google Scholar 

  7. Walmsley, R. M., Szostak, J. W. & Petes, T. D. Nature 302, 84–86 (1983).

    ADS  CAS  Article  Google Scholar 

  8. Shampay, J., Szostak, J. W. & Blackburn, E. H. Nature 310, 154–157 (1984).

    ADS  CAS  Article  Google Scholar 

  9. Bergold, P. J., Campbell, G. R., Littau, V. C. & Johnson, E. M. Cell 32, 1287–1299 (1983).

    CAS  Article  Google Scholar 

  10. Dancis, B. M. & Holmquist, G. P. J. theor. Biol. 78, 211–224 (1979).

    CAS  Article  Google Scholar 

  11. Formosa, T. & Alberts, B. M. Cell 47, 793–806 (1986).

    CAS  Article  Google Scholar 

  12. Heumann, J. M. Nucleic Acids Res. 3, 3167–3171 (1976).

    CAS  Article  Google Scholar 

  13. Morin, G. B. & Cech, T. R. Cell 52, 367–374 (1988).

    CAS  Article  Google Scholar 

  14. Walmsley, R. M., Chan, C. S. M., Tye, B.-K. & Petes, T. D. Nature 310, 157–160 (1984).

    ADS  CAS  Article  Google Scholar 

  15. Bernards, A., Michels, P. A. M., Lincke, G. R. & Borst, P. Nature 303, 592–597 (1983).

    ADS  CAS  Article  Google Scholar 

  16. Carson, M. J. & Hartwell, L. Cell 42, 249–257 (1985).

    CAS  Article  Google Scholar 

  17. Larsen, D. D., Spangler, E. A., Blackburn, E. H. Cell 50, 477–483 (1987).

    Article  Google Scholar 

  18. Shampay, J. & Blackburn, E. H. Proc. natn. Acad. Sci. U.S.A. 85, 534–538 (1988).

    ADS  CAS  Article  Google Scholar 

  19. Greider, C. W. & Blackburn, E. H. Cell 43, 405–413 (1985).

    CAS  Article  Google Scholar 

  20. Szostak, J. W. Cold Spring Harb. Symp. quant. Biol. 47, 1187–1194 (1983).

    Article  Google Scholar 

  21. Dunn, B., Szauter, P., Pardue, M. L. & Szostak, J. W. Cell 39, 191–201 (1984).

    CAS  Article  Google Scholar 

  22. Prakash, L. & Taillon-Miller, P. Curr. Genet. 2, 247–250 (1980).

    Google Scholar 

  23. Zamb, T. J. & Petes, T. D. Curr. Genet. 3, 125–132 (1981).

    CAS  Article  Google Scholar 

  24. Zakian, V. A., Blanton, H. M. & Dani, G. M. Curr. Genet. 9, 441–445 (1985).

    CAS  Article  Google Scholar 

  25. Henderson, E., Hardin, C. C., Walk, S. K., Tinoco, I. Jr & Blackburn, E. H. Cell 51, 899–908 (1987).

    CAS  Article  Google Scholar 

  26. Kolodner, R., Evans, D. H. & Morrison, P. T. Proc. natn. Acad. Sci. U.S.A. 84, 5560–5564 (1987).

    ADS  CAS  Article  Google Scholar 

  27. Smith, G. P. Science 191, 528–535 (1976).

    ADS  CAS  Article  Google Scholar 

  28. Chen, E. Y. & Seeburg, P. H. DNA 4, 165–170 (1985).

    CAS  Article  Google Scholar 

  29. McGraw, R. A. Analyt. Biochem. 143, 298–303 (1984).

    CAS  Article  Google Scholar 

  30. Din, N. & Engberg, J. J. molec. Biol. 134, 555–574 (1979).

    CAS  Article  Google Scholar 

  31. Stinchcomb, D. T., Thomas, M., Kelly, J., Selker, E. & Davis, R. W. Proc. natn. Acad. Sci. U.S.A. 77, 4559–4563 (1980).

    ADS  CAS  Article  Google Scholar 

  32. Henikoff, S. Meth. Enzym. 155, 156–165 (1987).

    CAS  Article  Google Scholar 

  33. Maniatis, T., Fritsch, E. F. & Sambrook, J. In Molecular Cloning: a Laboratory Manual (Cold Spring Harbor Laboratory, New York, 1982).

    Google Scholar 

  34. Spear, B. B. Chromosoma 77, 193–203 (1980).

    CAS  Article  Google Scholar 

  35. Sherman, F., Fink, G. R. & Lawrence, C. W. In Methods in Yeast Genetics, Laboratory Manual (Cold Spring Harbor Laboratory, New York, 1974).

    Google Scholar 

  36. Wahl, G. M., Stern, M. & Stark, G. R. Proc. natn. Acad. Sci. U.S.A. 76, 3683–3687 (1979).

    ADS  CAS  Article  Google Scholar 

  37. Kiss, G. B., Amin, A. A. & Pearlman, R. E. Molec. cell. Biol. 1, 535–543 (1981).

    CAS  Article  Google Scholar 

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Author information

Author notes

  1. Virginia A. Zakian: To whom correspondence should be addressed.

Affiliations

  1. Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, Washington, 98104, USA

    Ann F. Pluta & Virginia A. Zakian

  2. Department of Pathology, University of Washington, Seattle, Washington, 98195, USA

    Ann F. Pluta & Virginia A. Zakian

Authors
  1. Ann F. Pluta
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  2. Virginia A. Zakian
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Pluta, A., Zakian, V. Recombination occurs during telomere formation in yeast. Nature 337, 429–433 (1989). https://doi.org/10.1038/337429a0

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  • DOI: https://doi.org/10.1038/337429a0

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