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Transcriptional autoregulation of the proto-oncogene fos

Nature volume 334, pages 314–319 (1988)Cite this article

Abstract

Serum-induced transcription of the proto-oncogene fos is under negative feedback regulation mediated by the fos protein. The fos promoter region responsive to repression is also required for serum inducibility and binds a nucleoprotein complex in which the nuclear factor AP-1 is associated with fos protein.

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Author information

Affiliations

  1. Molecular Biology and Virology Laboratory, The Salk Institute, PO Box 85800, San Diego, California, 92138, USA

    Paolo Sassone-Corsi, John C. Sisson & Inder M. Verma

Authors
  1. Paolo Sassone-Corsi
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  2. John C. Sisson
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  3. Inder M. Verma
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Sassone-Corsi, P., Sisson, J. & Verma, I. Transcriptional autoregulation of the proto-oncogene fos. Nature 334, 314–319 (1988). https://doi.org/10.1038/334314a0

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