Figure 3 | Gene Therapy

Figure 3

From: Increased level and duration of expression in muscle by co-expression of a transactivator using plasmid systems

Figure 3

Effect of co-expression of serum response factor (SRF) on SkA promoter activity in murine gastronemius and tibialis muscle. Twenty micrograms of SkA-luciferase plasmid (pLC1072) and 5 μg of SRF expression plasmid (pSRF) or the control plasmid (pCGN) were co-formulated in 50 μl of saline and injected into gastrocnemius muscles. Half of the same plasmid dose was administered to the tibialis muscles of the same mice. Luciferase activity in the muscles was determined 2 days after injection. Each bar is the mean ± s.e.m (n = 10 muscles).

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