Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Confocal microscopy comes of age

Scanning confocal optical microscopy offers increased resolution and superior rejection of out-of-focus signals for epifluorescence imaging of biological material.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1. Agard, D.A. & Sedat, J.W. Nature302,676–681 (1983). 2. Minsky, M. U.S. Patent no. 3013467. 3. Wilson, T. & Sheppard, C.J.R. Theory and Practice of Scanning Optical Microscopy, (Academic, New York, 1984). 4. Brakenhoff,G.J.,Blom,P. &Barends,P.J.7. Microsc. Ill, 219–232(1979). 5. Wijneandts van Resant, R.W. et al. J. Microsc. 138, 29–34 (1985). 6. Petran, M., Hadravsky, J. Benes, J., Kucera, R. & Boyd, A. Proc. R. Microsc. Soc. 20,125–139 (1985). 7. Carlsson, K. etal. Optics Lett. 10, 53–55 (1985). 8. White, J.G., Amos, W.B. & Fordham, M. /. Cell Biol. (in the press). 9. Tsien, R.Y. & Poenie, M. Trends biochem. Sci. 11,450–455 (1986).

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

White, J., Amos, W. Confocal microscopy comes of age. Nature 328, 183–184 (1987).

Download citation

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing