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Computer-assisted model building

Nature volume 321, pages 93–94 (1986)Cite this article

Developments in computer graphics and distance geometry have provided important tools for comparative model building of protein structures.

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References

  1. Cohen, F.E., Abarbanel, R.M., Kuntz, I.D. & Fletterick, R.J. Biochemistry 22, 4894–4904 (1983).

    Article  CAS  Google Scholar 

  2. Langridge, R., Ferrin, T.E., Kuntz, I.D. & Connolly, M.L. Science 211, 661–666 (1981).

    Article  ADS  CAS  Google Scholar 

  3. Ondetti, M.A., Rubin, B. & Cushman, D.W. Science 196, 441–444 (1977).

    Article  ADS  CAS  Google Scholar 

  4. Beddell, C.R., Goodford, P.J., Norringotn, F.E., Wilkinson, S. & Wootton, R. Brit. J. Pharmac. 57, 201–209 (1976).

    Article  CAS  Google Scholar 

  5. Blundell, T., Sibanda, B.L. & Pearl, L. Nature 304, 273–275 (1983).

    Article  ADS  CAS  Google Scholar 

  6. Sibanda, B.L. et al. FEBS Letters 174, 102–111 (1984).

    Article  CAS  Google Scholar 

  7. Greer, J., J. molec. Biol. Biol. 153, 1027–1042 (1981).

    Article  CAS  Google Scholar 

  8. Feldman, R.J. et al. in Macromolecular Structure and Specificity (eds Venkataraghavan, B., Feldman, R.J.) 12–43 (New York Academy of Sciences, New York, 1985).

    Google Scholar 

  9. Crippen, G.M. in Chemometric Research Studies Series Vol. 1 (ed. Baudan, D.) 1–58 (Wiley. New York 1981).

    Google Scholar 

  10. O'Neil, K.T. & DeGrado, W.F. Proc. natn. Acad. Sci. U.S.A. 82, 4954–4958, (1985).

    Article  ADS  CAS  Google Scholar 

  11. Read, R.J., Brayer, G.D., Jurasek, L. & James, M.N.G. Biochemistry 23, 6570–6575 (1984).

    Article  CAS  Google Scholar 

  12. Dijkstra, B.W., Weijer, W.J. & Wierenga, R.K. FEBS Lett. 164, 25–27(1983).

Download references

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Authors and Affiliations

  1. Biomedical Products Department, Medicinal Chemistry Division, E.I. DuPont DeNemours Co, Wilmington, Delaware, 19898, USA

    W. C. Ripka

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  1. W. C. Ripka
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Ripka, W. Computer-assisted model building. Nature 321, 93–94 (1986). https://doi.org/10.1038/321093a0

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