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Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae

Nature volume 312, pages 616–620 (1984)Cite this article

A Corrigendum to this article was published on 01 October 1985

Abstract

The nucleotide sequence of a complete genomic clone for the histidine-rich protein of Plasmodium lophurae has been determined. The deduced amino acid sequence of the mature protein shows numerous tandemly repeated units preceded by a signal and a pro peptide. The gene is interrupted by an intron with a separate exon coding for the signal peptide. The signal peptide-encoding exon detects multiple cross-hybridizing sequences in the parasite genome.

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Authors and Affiliations

  1. The Dewitt Wallace Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, USA

    Jeffrey V. Ravetch & Amalia Pavlovec

  2. Laboratory of Cell Biology, The Rockefeller University, New York, New York, 10021, USA

    Roslyn Feder & Gunter Blobel

Authors
  1. Jeffrey V. Ravetch
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  2. Roslyn Feder
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  3. Amalia Pavlovec
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  4. Gunter Blobel
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Ravetch, J., Feder, R., Pavlovec, A. et al. Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae. Nature 312, 616–620 (1984). https://doi.org/10.1038/312616a0

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