Abstract
T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor β-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.
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Yoshikai, Y., Anatoniou, D., Clark, S. et al. Sequence and expression of transcripts of the human T-cell receptor β- chain genes. Nature 312, 521–524 (1984). https://doi.org/10.1038/312521a0
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DOI: https://doi.org/10.1038/312521a0
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