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DNA sequence and expression of the B95-8 Epstein—Barr virus genome

Abstract

The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from these promoters have been assigned to the latent or early/late productive virus cycles. Likely protein-coding regions have been identified and three of these have been shown to encode a ribonucleotide reductase, a DNA polymerase and two surface glycoproteins.

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Baer, R., Bankier, A., Biggin, M. et al. DNA sequence and expression of the B95-8 Epstein—Barr virus genome. Nature 310, 207–211 (1984). https://doi.org/10.1038/310207a0

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