Table 6 Reduction of SSS by oral THC (Phase 1) and rectal THC-HS (Phase 2) (ANOVA with repeated measures)

From: The treatment of spasticity with Δ9-tetrahydrocannabinol in persons with spinal cord injury

  Phase 1 open label oral THC Phase 2 open label rectal THC-HS
  N=15 N=7
Baseline 16.7 (±7.6) 22.7 (±11.7)
Day 1 7.8 (±7.0)** 9.9 (±8.2)*
Day 8 8.9 (±6.8)** 12.0 (±8.1)*
Day 43 8.9 (±7.1)* 9.2 (±9.3)*
  1. Day 1: SSS as measured 2 h after a single dose of 10 mg oral THC or 10 mg rectal THC-HS
  2. Days 8 and 43: SSS as measured 2 h after administration of the individual THC doses
  3. *P<0.05 (compared to baseline)
  4. **P<0.001 (compared to baseline)