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Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

Nature volume 309, pages 763767 (28 June 1984) | Download Citation

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Abstract

cDNA clones specifying the murine granulocyte–macrophage colony stimulating factor have been isolated. This haematopoietic growth factor is encoded by a unique gene specifying a messenger RNA of 1,200 nucleotides and a polypeptide of 118 amino acids. It bears no structural similarity to the functionally related factor, interleukin-3, described recently.

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Affiliations

  1. Melbourne Tumour Biology Branch, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria 3050, Australia

    • Nicholas M. Gough
    • , Jill Gough
    • , Dianne Grail
    • , Antony W. Burgess
    •  & Ashley R. Dunn
  2. The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia

    • Donald Metcalf
    • , Anne Kelso
    •  & Nicos A. Nicola

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https://doi.org/10.1038/309763a0

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