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Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

Nature volume 307, pages 708–714 (1984)Cite this article

Abstract

Two simian virus 40 transcriptional promoter elements, the 72-base pair (bp) repeat and the 21-bp repeat region, induce chromatin structures of increased DNase I sensitivity when transposed elsewhere in the viral genome. The induction of a sufficiently long stretch of DNase I-sensitive chromatin leads to the appearance of a visible nucleosome-free region.

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Authors and Affiliations

  1. Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Unité 184 de Biologie Moléculaire et de Génie Génétique de l'INSERM, Faculté de Médecine, 11 rue Humann, 67085, Strasbourg Cedex, France

    Jan Jongstra, Tim L. Reudelhuber, Pierre Oudet, Christophe Benoist, Chi-Bom Chae, Jean-Marc Jeltsch, Diane J. Mathis & Pierre Chambon

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  1. Jan Jongstra
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  2. Tim L. Reudelhuber
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Jongstra, J., Reudelhuber, T., Oudet, P. et al. Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements. Nature 307, 708–714 (1984). https://doi.org/10.1038/307708a0

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