Abstract
The following is the lecture delivered by the author in Stockholm on 8 December 1981 when he received the Nobel Prize in Medicine, which he shared with Roger Sperry and David H. Hubel The article is published here with permission from the Nobel Foundation and will also be included in the complete volume of Les Prix Nobel en 1981 as well as in the series Nobel Lectures (in English) lished by Elsevier.
Access options
Subscribe to Journal
Get full journal access for 1 year
$199.00
only $3.90 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Rent or Buy article
Get time limited or full article access on ReadCube.
from$8.99
All prices are NET prices.
References
- 1
Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond., 160, 106 (1962).
- 2
von Senden, M. Space and Sight (The Free Press. Glencoe, 1960).
- 3
Hebb, D. O. The Organization of Behavior (Wiley, New York, 1949).
- 4
McCleary, R. A. Genetic and Experimental Factors in Perception (Scott Foresman, Glen-view, 1970).
- 5
Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 148, 574 (1959).
- 6
Wiesel, T. N. & Hubel, D. H. J. Neurophysiol. 26, 1003 (1963).
- 7
Wiesel, T. N. & Hubel, D. H. J. Neurophysiol. 26, 978 (1963).
- 8
Hubel, D. H. & Wiesel, T. N. J. Neurophysiol. 26, 994 (1963).
- 9
Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 206, 419 (1970).
- 10
Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 195, 215 (1968).
- 11
Wiesel, T. N. & Hubel, D. H. Symp. Int. Un. of physiol. Sci. Abstr. P., Munich (1971).
- 12
Baker, F. H., Grigg, P. & von Noorden, G. K. Brain Res. 66, 185 (1974).
- 13
Hubel, D. H., Wiesel, T. N. & LeVay, S. Phil. Trans. Soc. Lond. B278, 377 (1977).
- 14
Blakemore, C., Garey, L. J. & Vital-Durand, F. J. Physiol., Lond. 283, 223 (1978).
- 15
LeVay, S., Wiesel, T. N. & Hubel, D. H. J. comp. Neurol 191, 1 (1980).
- 16
Hubel, D. H. & Wiesel, T. N. J. comp. Neurol. 146, 421 (1972).
- 17
Hubel, D. H. & Wiesel, T. N. J. comp. Neurol. 158, 267 (1974).
- 18
Wiesel, T. N., Hubel, D. H. & Lam, D. Brain Res. 79, 273 (1974).
- 19
LeVay, S., Hubel, D. H. & Wiesel, T. N. J. comp. Neurol. 159, 559 (1975).
- 20
Hubel, D. H. Nature 299, 515–524 (1982).
- 21
Hubel, D. H. & Wiesel, T. N. Proc. R. Soc. B198, 1 (1977).
- 22
Hubel, D. H. & Wiesel, T. N. J. Neurophysiol. 28, 229 (1965).
- 23
Barlow, H. B. Nature 258, 199 (1975).
- 24
Pettigrew, J. D. in Neuronal Plasticity (ed. Cotman, C.) 311–330 (Raven, New York, 1978).
- 25
Movshon, J. A. & von Sluyter, R. C. A. Rev. Psychol. 32, 477 (1981).
- 26
Wiesel, T. N. & Raviola, E. Nature 266, 66 (1977).
- 27
Guillery, R. W. & Stelzner, D. J. J. comp. Neurol. 139, 413 (1970).
- 28
Crawford, M. L. J., Blake, R., Cool, S. J. & von Noorden, G. K. Brain Res. 84, 150 (1975).
- 29
Blakemore, C. & von Sluyter, R. C. J. Physiol., Lond. 237, 195 (1974).
- 30
Arden, G. B. & Barnard, W. M. Trans. opthal. Soc. U.K. 99, 419 (1979).
- 31
Vaegan, D. T. Trans. ophthal. Soc. U.K. 99, 432 (1979).
- 32
von Noorden, G. K. Am. J. ophthal. 92, 416 (1981).
- 33
Dews, P. B. & Wiesel, T. N. J. Physiol., Lond. 206, 437 (1970).
- 34
Ganz, L., Hirsch, H. V. B. & Tieman, S. B. Brain Res. 44, 547 (1972).
- 35
Mitchell, D. E., Cynader, M. & Movshon, J. A. J. comp. Neurol, 176, 53 (1977).
- 36
Olson, C. R. & Freeman, R. D. J. Neurophysiol. 41, 65 (1978).
- 37
Awaya, S., Sugawara, M. & Miyake, S. Trans. ophthal. Soc. U.K. 99, 447 (1979).
- 38
Odom, J. V., Hoyt, C. S. & Marg, E. Archs Ophthal. 99, 1412 (1981).
- 39
Beller, R., Hoyt, S., Marg, E. & Odom, J. V. Am. J. Ophthal. 91, 559 (1981).
- 40
Jacobson, S. G., Mohindra, J. & Held, R. Br. J. Ophthal. 65, 727 (1981).
- 41
Blakemore, C., Vital-Durand, F. & Garey, J. Proc. R. Soc. B213, 399 (1981).
- 42
Swindale, N. V., Vital-Durand, F. & Blakemore, C. Proc. R. Soc. B213, 435 (1981).
- 43
Wiesel, T. N. & Hubel, D. H. J. Neurophysiol. 28, 1029 (1965).
- 44
Wiesel, T. N. & Hubel, D. H. J. comp. Neurol. 158, 807 (1974).
- 45
Guillery, R. W. J. comp. Neurol. 144, 117 (1972).
- 46
Guillery, R. W. J. comp. Neurol. 148, 417 (1973).
- 47
Hubel, D. H. & Weisel, T. N. J. Neurophysiol. 28, 1041 (1965).
- 48
Yinon, U. Expl Brain Res. 26, 151 (1976).
- 49
Crawford, M. L. J. & von Noorden, G. K. Invest. Ophthal. 18, 496 (1979).
- 50
Jacobson, S. G. & Ikeda, H. Expl Brain Res. 34, 11 (1979).
- 51
Singer, W., Rauschecker, J. & Werth, R. Brain Res. 134, 568 (1977).
- 52
Wilson, J. R., Webb, S. V. & Sherman, S. M. Brain Res. 136, 277 (1977).
- 53
Stent, G. S. Proc. natn. Acad. Sci. U.S.A. 70, 997 (1973).
- 54
Changeux, J.-P. & Danchin, A. Nature 264, 705 (1976).
- 55
Ikeda, H. & Wright, M. J. Expl Brain Res. 25, 63 (1976).
- 56
Hirsch, H. V. B. & Spinelli, D. N. Science, 168, 869 (1970).
- 57
Blakemore, C. & Cooper, G. F. Nature 228, 477 (1970).
- 58
Cynader, M. & Mitchell, D. E. Nature 270, 177 (1977).
- 59
Rauschecker, J. P. & Singer, W. Nature 280, 58 (1979).
- 60
Buisseret, P. & Imbert, M. J. Physiol., Lond. 255, 511 (1976).
- 61
Marty, R. Archs Anat. Microsc. Morphol. Exp. 52, 129 (1962).
- 62
Cragg, B. G. J. comp. Neurol. 160, 147 (1975).
- 63
Pettigrew, J. D. J. Physiol., Lond. 237, 49 (1974).
- 64
Blakemore, C. & von Sluyter, R. C. J. Physiol., Lond. 248, 663 (1975).
- 65
Sherk, H. & Stryker, M. P. J. Neurophysiol. 39, 63 (1976).
- 66
Singer, W. & Tretter, F. J. Neurophysiol. 39, 613 (1976).
- 67
Des Rosiers, M. H. et al. Science 200, 447 (1978).
- 68
Rakic, P. Phil. Trans. R. Soc. B278, 245 (1977).
- 69
LeVay, S., Stryker, M. P. & Shatz, C. J. J. comp. Neurol. 179, 223 (1978).
- 70
Swindale, N. V. Nature 290, 332 (1981).
- 71
LeVay, S. & Stryker, M. P. Soc. Neurosci. Symp. 4, 83 (1979).
- 72
Ferster, D. & LeVay, S. J. comp. Neurol. 182, 923 (1978).
- 73
Gilbert, C. & Wiesel, T. N. Nature 280, 120 (1979).
- 74
Kasamatsu, T. & Pettigrew, J. D. J. comp. Neurol. 185, 139 (1979).
- 75
Enroth-Cugell, C. & Robson, J. G. J. Physiol., Lond. 182, 923 (1966).
Author information
Affiliations
Rights and permissions
About this article
Cite this article
Wiesel, T. Postnatal development of the visual cortex and the influence of environment. Nature 299, 583–591 (1982). https://doi.org/10.1038/299583a0
Issue Date:
Further reading
-
Learning-Dependent Dendritic Spine Plasticity Is Reduced in the Aged Mouse Cortex
Frontiers in Neural Circuits (2020)
-
A human-in-the-loop deep learning paradigm for synergic visual evaluation in children
Neural Networks (2020)
-
Development of Brain Networks In Utero: Relevance for Common Neural Disorders
Biological Psychiatry (2020)
-
The developmental support hypothesis: adaptive plasticity in neural development in response to cues of social support
Philosophical Transactions of the Royal Society B: Biological Sciences (2020)
-
Homeoprotein transduction in neurodevelopment and physiopathology
Science Advances (2020)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.