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The operator-binding domain of λ repressor: structure and DNA recognition

Abstract

The structure of the operator-binding domain of the λ repressor has been determined at 3.2 Å resolution. This domain contains an extended N-terminal arm and five α-helices. Model-building studies of the repressor–operator complex suggest that α-helices, especially the N-terminal parts of these helices, may provide a useful surface for protein–DNA interactions.

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Pabo, C., Lewis, M. The operator-binding domain of λ repressor: structure and DNA recognition. Nature 298, 443–447 (1982). https://doi.org/10.1038/298443a0

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