Abstract
Recently, an extra chromosome 12 has been reported to occur with high frequency in peripheral blood lymphocytes from patients with chronic B-cell lymphocytic leukaemia (B-CLL)1,2. Here we report a unique chromosomal abnormality, which suggests that the segment q13 to q22 on chromosome 12 carries the important genes that are duplicated in those lymphoproliferative disorders characterized by trisomy for this chromosome.
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Gahrton, G., Robert, KH., Friberg, K. et al. Cytogenetic mapping of the duplicated segment of chromosome 12 in lymphoproliferative disorders. Nature 297, 513–514 (1982). https://doi.org/10.1038/297513a0
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DOI: https://doi.org/10.1038/297513a0
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