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Structure of genes for membrane and secreted murine IgD heavy chains

Nature volume 296, pages 410–415 (1982)Cite this article

Abstract

We have sequenced secreted and membrane terminal exons of the murine immunoglobulin δ chain. The putative transmembranal exon is strikingly similar to that of the μ chain and the internal cytoplasmic exon codes for exactly the same two amino acids, valine and lysine. A third potential exon was found between S and M exons that could code for yet another hydrophilic carboxyl terminus termed δX.

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Author information

Authors and Affiliations

  1. Department of Microbiology, University of Texas Southwestern Medical School, Dallas, Texas, 75235, USA

    Hwei-Ling Cheng & Philip W. Tucker

  2. Department of Genetics, University of Wisconsin, Madison, Wisconsin, 53706, USA

    Frederick R. Blattner

  3. Laboratory Immunology (NIAID), National Institutes of Health, Bethesda, Maryland, 20205, USA

    Leona Fitzmaurice

  4. Laboratory of Cell Biology (NCI), National Institutes of Health, Bethesda, Maryland, 20205, USA

    J. Frederic Mushinski

Authors
  1. Hwei-Ling Cheng
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  2. Frederick R. Blattner
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  3. Leona Fitzmaurice
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  4. J. Frederic Mushinski
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  5. Philip W. Tucker
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Cheng, HL., Blattner, F., Fitzmaurice, L. et al. Structure of genes for membrane and secreted murine IgD heavy chains. Nature 296, 410–415 (1982). https://doi.org/10.1038/296410a0

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