Abstract
X-ray diffraction data from polyoma capsid crystals were phased by refinement of low-resolution starting models to obtain a self-consistent structural solution. The unexpected result that the hexavalent morphological unit is a pentamer shows that specificity of bonding is not conserved among the protein subunits in the icosahedrally symmetric capsid.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Adolph, K. W. et al. Science 203, 1117–1119 (1979).
Klug, A. J. molec. Biol. 11, 424–431 (1965).
Finch, J. T. Gen. Virol. 24, 359–364 (1974).
Caspar, D. L. D. & Klug, A. Cold Spring Harb. Symp. quant. Biol. 27, 1–24 (1962).
Harrison, S. C., Olson, A. J., Schutt, C. E., Winkler, F. K. & Bricogne, G. Nature 276, 368–373 (1978).
Abad-Zapatero, C. et al. Nature 286, 33–39 (1980).
Finch, J. T. & Klug, A. J. molec. Biol. 13, 1–12 (1965).
Kiselev, N. A. & Klug, A. J. molec. Biol. 40, 155–171 (1969).
Tooze, J. (ed.) DNA Tumour Viruses (Cold Spring Harbor, New York, 1980).
Murakami, W. T. & Schaffhausen, B. S. 25th a. M.D. Anderson Symp., 43–62 (Williams & Wilkins, Baltimore, 1974).
Murakami, W. T., Fine, R., Harrington, M. R. & Ben Sassan, Z. J. molec. Biol. 36, 153–166 (1968).
Murakami, W. T. Science 142, 56–57 (1963).
Harrison, S. C. J. appl. Crystallogr. 1, 84–90 (1968).
Johnson, J. E., Akimoto, T., Suck, D., Rayment, I. & Rossmann, M. G. Virology 75, 394–400 (1976).
Bricogne, G. Acta crystallogr. A32, 832–847 (1976).
Bricogne, G. Acta crystallogr. A30, 395–405 (1974).
Johnson, J. E. Acta crystallogr. B34, 576–577 (1978).
Sim, G. A. Acta crystallogr. 12, 813–815 (1959).
Friedmann, T. Proc. natn. Acad. Sci. U.S.A. 68, 2574–2578 (1971).
Deininger, P., Esty, A., LaPorte, P. & Friedmann, T. Cell 18, 771–779 (1979).
Soeda, E., Arrand, J. R., Smolar, N., Walsh, J. E. & Griffin, B. E. Nature 283, 445–453 (1980).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rayment, I., Baker, T., Caspar, D. et al. Polyoma virus capsid structure at 22.5 Å resolution. Nature 295, 110–115 (1982). https://doi.org/10.1038/295110a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/295110a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
