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Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

Nature volume 291, pages 122–126 (1981)Cite this article

Abstract

Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.

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Author information

Authors and Affiliations

  1. Department of Microbiology, Moyne Institute, Trinity College, Dublin, 2, Ireland

    Michael Kehoe & Gordon Dougan

  2. Institute for Research on Animal Diseases, Compton, Newbury, Berkshire, UK

    Richard Sellwood

  3. Department of Microbiology, Virginia Commonwealth University, Richmond, Virginia, 23298, USA

    Patricia Shipley

Authors
  1. Michael Kehoe
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  2. Richard Sellwood
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  3. Patricia Shipley
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  4. Gordon Dougan
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Kehoe, M., Sellwood, R., Shipley, P. et al. Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli. Nature 291, 122–126 (1981). https://doi.org/10.1038/291122a0

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