Abstract
The dauer larva of Caenorhabditis elegans is a developmentally arrested stage induced by starvation or overcrowding. Mutant genes controlling the ability to form dauer larvae interact in a way which allows them to be ordered in a pathway. Mutant phenotypes suggest that the pathway corresponds to neural processing of environmental stimuli.
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References
- 1
Beadle, G. W. & Ephrussi, B. Genetics 22, 76–86 (1937).
- 2
Brenner, S. Genetics 77, 71–94 (1974).
- 3
von Ehrenstein, G. & Schierenberg, E. in Nematodes as Biological Models Vol 1 (ed. Zuckerman, B. M.) 2–71 (Academic, New York, 1980).
- 4
White, J. G., Southgate, E., Thomson, J. N. & Brenner, S. Phil. Trans. R. Soc. B275, 327–348 (1976).
- 5
Sulston, J. E., Albertson, D. G. & Thomson, J. N. Devl Biol. 78, 542–576 (1980).
- 6
Bovien, P. Vidensk. Meddr dansk. naturh. Foren. 101, 1–113 (1937).
- 7
Cassada, R. C. & Russell, R. L. Devl Biol. 46, 326–342 (1975).
- 8
Cassada, R. C. & Russell, R. L. Fedn Proc. 33, 1476 (1974).
- 9
Klass, M. & Hirsh, D. Nature 260, 523–525 (1976).
- 10
Evans, A. A. F. & Perry, R. N. in The Organization of Nematodes (ed. Croll, N. A.) 383–424 (Academic, New York, 1976).
- 11
Albert, P. S., Brown, S. & Riddle, D. L. J. comp. Neural, (in the press).
- 12
Swanson, M. M. & Riddle, D. L. Devl Biol. (in the press).
- 13
Riddle, D. L. Stadler Genet. Symp. 9, 101–120 (1977).
- 14
Cassada, R. C. in Developmental Biology: Pattern Formation and Gene Regulation (eds McMahon, D. M. & Fox, C. F.) 539–547 (Benjamin, Menlo Park, 1975).
- 15
Lewis, J. A. & Hodgkin, J. A. J. comp. Neurol. 172, 489–510 (1977).
- 16
Ward, S. Proc. natn. Acad. Sci. U.S.A. 70, 817–821 (1973).
- 17
Ward, S., Thomson, N., White, J. G. & Brenner, S. J. comp. Neurol. 160, 313–338 (1975).
- 18
Ware, R. W., Clark, D., Grassland, K. & Russell, R. L. J. comp. Neurol. 162, 71–110 (1975).
- 19
Herman, R. K. & Horvitz, H. R. in Nematodes as Biological Models Vol 1 (ed. Zuckerman, B. M.) 228–261 (Academic, New York, 1980).
- 20
Wood, W. B., Edgar, R. S., King, J., Lielausis, I. & Henninger, M. Fedn Proc. 27, 1160–1166 (1968).
- 21
Herman, R. K., Horvitz, H. R. & Riddle, D. L. Genet. Maps 1, 183–193 (1980).
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Riddle, D., Swanson, M. & Albert, P. Interacting genes in nematode dauer larva formation. Nature 290, 668–671 (1981). https://doi.org/10.1038/290668a0
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