Interacting genes in nematode dauer larva formation

Abstract

The dauer larva of Caenorhabditis elegans is a developmentally arrested stage induced by starvation or overcrowding. Mutant genes controlling the ability to form dauer larvae interact in a way which allows them to be ordered in a pathway. Mutant phenotypes suggest that the pathway corresponds to neural processing of environmental stimuli.

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References

  1. 1

    Beadle, G. W. & Ephrussi, B. Genetics 22, 76–86 (1937).

  2. 2

    Brenner, S. Genetics 77, 71–94 (1974).

  3. 3

    von Ehrenstein, G. & Schierenberg, E. in Nematodes as Biological Models Vol 1 (ed. Zuckerman, B. M.) 2–71 (Academic, New York, 1980).

  4. 4

    White, J. G., Southgate, E., Thomson, J. N. & Brenner, S. Phil. Trans. R. Soc. B275, 327–348 (1976).

  5. 5

    Sulston, J. E., Albertson, D. G. & Thomson, J. N. Devl Biol. 78, 542–576 (1980).

  6. 6

    Bovien, P. Vidensk. Meddr dansk. naturh. Foren. 101, 1–113 (1937).

  7. 7

    Cassada, R. C. & Russell, R. L. Devl Biol. 46, 326–342 (1975).

  8. 8

    Cassada, R. C. & Russell, R. L. Fedn Proc. 33, 1476 (1974).

  9. 9

    Klass, M. & Hirsh, D. Nature 260, 523–525 (1976).

  10. 10

    Evans, A. A. F. & Perry, R. N. in The Organization of Nematodes (ed. Croll, N. A.) 383–424 (Academic, New York, 1976).

  11. 11

    Albert, P. S., Brown, S. & Riddle, D. L. J. comp. Neural, (in the press).

  12. 12

    Swanson, M. M. & Riddle, D. L. Devl Biol. (in the press).

  13. 13

    Riddle, D. L. Stadler Genet. Symp. 9, 101–120 (1977).

  14. 14

    Cassada, R. C. in Developmental Biology: Pattern Formation and Gene Regulation (eds McMahon, D. M. & Fox, C. F.) 539–547 (Benjamin, Menlo Park, 1975).

  15. 15

    Lewis, J. A. & Hodgkin, J. A. J. comp. Neurol. 172, 489–510 (1977).

  16. 16

    Ward, S. Proc. natn. Acad. Sci. U.S.A. 70, 817–821 (1973).

  17. 17

    Ward, S., Thomson, N., White, J. G. & Brenner, S. J. comp. Neurol. 160, 313–338 (1975).

  18. 18

    Ware, R. W., Clark, D., Grassland, K. & Russell, R. L. J. comp. Neurol. 162, 71–110 (1975).

  19. 19

    Herman, R. K. & Horvitz, H. R. in Nematodes as Biological Models Vol 1 (ed. Zuckerman, B. M.) 228–261 (Academic, New York, 1980).

  20. 20

    Wood, W. B., Edgar, R. S., King, J., Lielausis, I. & Henninger, M. Fedn Proc. 27, 1160–1166 (1968).

  21. 21

    Herman, R. K., Horvitz, H. R. & Riddle, D. L. Genet. Maps 1, 183–193 (1980).

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