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Nucleotide sequences at host–proviral junctions for mouse mammary tumour virus

Nature volume 289, pages 253–258 (1981)Cite this article

Abstract

Proviruses cloned from rat cells infected with mouse mammary tumour virus, a B-type retrovirus regulated by glucocorticoid hormones, show the structural features of transposable elements: short inverted repeats conclude long direct repeats at the ends of viral DNA, and short sequences of cellular DNA are duplicated during integration and flank each provirus. The integrative mechanism joins a precise site in viral DNA to non-homologous sites in host DNA.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, University of California, San Francisco, California, 94143

    John E. Majors & Harold E. Varmus

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  1. John E. Majors
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  2. Harold E. Varmus
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Majors, J., Varmus, H. Nucleotide sequences at host–proviral junctions for mouse mammary tumour virus. Nature 289, 253–258 (1981). https://doi.org/10.1038/289253a0

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