Abstract
The β-adrenergic receptor (R) and the GTP binding protein (G) with which the receptor interacts were obtained in separate soluble fractions. Their recombination produced a hormone responsive system. In the presence of hormone the encounter of R with G in the reconstituted membrane occurs much faster than the subsequent R-induced activation of G.
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Citri, Y., Schramm, M. Resolution, reconstitution and kinetics of the primary action of a hormone receptor. Nature 287, 297–300 (1980). https://doi.org/10.1038/287297a0
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DOI: https://doi.org/10.1038/287297a0
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