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DNA N-glycosylases and UV repair

Nature volume 287, pages 203–208 (1980)Cite this article

Abstract

Repair of some DNA photoproducts can be mediated by glycosylic bond hydrolysis. Thus, Escherichia coli endonuclease III releases 5,6-hydrated thymines as free bases, while T4 UV endonuclease releases one of two glycosylic bonds holding pyrimidine dimers in DNA. In contrast, uninfected E. coli apparently does not excise pyrimidine dimers via a DNA glycosylase.

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Authors and Affiliations

  1. Department of Biochemistry, University of California, Berkeley, California, 94720

    Bruce Demple & Stuart Linn

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  1. Bruce Demple
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  2. Stuart Linn
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Demple, B., Linn, S. DNA N-glycosylases and UV repair. Nature 287, 203–208 (1980). https://doi.org/10.1038/287203a0

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