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A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces

Abstract

Selectable plasmid vectors that contain a gene encoding resistance to the antibiotic methylenomycin A and that are suitable for the cloning of endonuclease-generated DNA fragments in Streptomyces species have been constructed and characterised.

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Bibb, M., Schottel, J. & Cohen, S. A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces. Nature 284, 526–531 (1980). https://doi.org/10.1038/284526a0

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