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Chicken lens crystallin DNA sequences show at least two δ-crystallin genes

Abstract

Restriction analysis of chicken DNA using probes derived from a cloned cDNA and analysis of cloned genomic DNA fragments containing δ-crystallin gene sequences have indicated the presence of at least two non-allelic genes for δ-crystallin, the first and principal crystallin synthesised in the embryonic chicken lens. Electron microscopic analyses of three cloned genomic fragments revealed that the δ-crystallin mRNA gene sequences are interrupted at least 14 times in one of the δ-crystallin genes.

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