Abstract
Previous analyses of carbonaceous chondrites have demonstrated the presence of the biologically significant purines adenine, guanine, hypoxanthine and xanthine1–3. To date, however, no pyrimidine of biological importance has been reported. An earlier report4 of a fraction extracted from the Murray meteorite showing ‘cytosine-like’ spectral characteristics was later shown to be due to an artefact of the analytical method5,6. Some unusual pyrimidines which have no known biological function were reported in extracts from the Murchison, Murray and Orgueil carbonaceous chondrites7. However, these results have not been replicated and are now thought to have been due to artefacts2,3. Because of the reported synthesis of the pyrimidines uracil, thymine and cytosine in Fischer-Tropsch-type reactions8,9 and the suggestion that such reactions may have been of significance in the production of organic material in meteorites9,10, we have reinvestigated the possible occurrence of pyrimidines in extracts from the Murchison, Murray and Orgueil carbonaceous meteorites using specific fractionation techniques and high-sensitivity analysis. The pyrimidines uracil, thymine and cytosine, together with the purines adenine and guanine are, of course, the building blocks of terrestrial genetic inheritance. Therefore their presence or absence in meteorites is also of considerable interest to theories of chemical evolution and the origin of life. We report here the positive identification of uracil in water and formic acid extracts of all three meteorites.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hayatsu, R. Science 146, 1291–1293 (1964).
Hayatsu, R., Studier, M. H., Moore, L. P. & Anders, E. Geochim. cosmochim. Acta 39, 471–488 (1975).
Van der Velden, W. & Schwartz, A. W. Geochim. cosmochim. Acta 41, 961–968 (1977)
Calvin, M. Chem. Engng News 39, 96–104 (1961).
Oró, J. Nature 197, 756–758 (1963).
Kaplan, I. R., Degens, E. T. & Reuter, J. H. Geochim. cosmochim. Acta 27, 805–834 (1963).
Folsome, C. E., Lawless, J. G., Romiez, M. & Ponnamperuma, C. Geochim. cosmochim. Acta 37, 455–465 (1973).
Hayatsu, R., Studier, M. H., Oda, A., Fuse, K. & Anders, E. Geochim. cosmochim. Acta 32, 175–190 (1968).
Hayatsu, R., Studier, M. H., Matsuoka, S. & Anders, E. Geochim. cosmochim. Acta 36, 555–571 (1972).
Anders, E., Hayatsu, R. & Studier, M. H. Science 182, 781–790 (1973).
Van der Velden, W. & Schwartz, A. W. Science 185, 691–693 (1974).
Van der Velden, W. & Schwartz, A. W. Environmental Biogeochemistry (ed. Nriagu, J. O.) 175–183 (Ann Arbor Science, Ann Arbor, 1976).
Van der Velden, W. & Schwartz, A. W. Chem. Geol. 18, 273–284 (1976).
Dungworth, G., Thijssen, M., Zuurveld, J. Van der Velden, W. & Schwartz, A. W. Chem. Geol. 19, 295–308 (1977).
Yoshino, D., Hayatsu, R. & Anders, E. Geochim. cosmochim. Acta 35, 927–938 (1971).
Hayatsu, R., Studier, M. H. & Anders, E. Geochim. cosmochim. Acta 35, 939–951 (1971).
Cronin, J. R. & Moore, C. B. Science 172, 1327–1329 (1971).
Kvenvolden, K. A. et al. Nature 228, 923–926 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Stoks, P., Schwartz, A. Uracil in carbonaceous meteorites. Nature 282, 709–710 (1979). https://doi.org/10.1038/282709a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/282709a0
This article is cited by
-
Uracil in the carbonaceous asteroid (162173) Ryugu
Nature Communications (2023)
-
Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites
Nature Communications (2022)
-
The RNA i-Motif in the Primordial RNA World
Origins of Life and Evolution of Biospheres (2019)
-
Astrobiology and the Possibility of Life on Earth and Elsewhere…
Space Science Reviews (2017)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.