Abstract
Binding of distamycin induces a cooperative transition of calf thymus DNA to a new form with higher affinity for the drug and altered structural properties.
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References
Bourgeois, S. & Pfahl, M. Adv. Protein Chem. 30, 1–99 (1976).
Hirsh, J. & Schleif, R. Cell 11, 545–550 (1977).
Müller, W. & Crothers, D. M. J. molec. Biol. 35, 251–290 (1968).
Bauer, W. & Vinograd, J. J. molec. Biol. 47, 419–435 (1970).
Crothers, D. M. Biopolymers 6, 575–584 (1968).
Sobell, H. M., Tsai, C. C., Jain, S. C. & Gilbert, S. G. J. molec. Biol. 114, 333–365 (1977).
Pohl, F., Jovin, T. M., Baehr, W. & Holbrook, J. J. Proc. natn. Acad. Sci. U.S.A. 69, 3805–3809 (1972).
Burd, J. F., Wartell, R. M., Dodgson, J. B. & Wells, R. D. J. biol. Chem. 250, 5109–5113 (1975).
Burd, J. F., Larson, J. E. & Wells, R. D. J. biol. Chem. 250, 6002–6007 (1975).
Hahn, F. E. in Antibiotics Vol. 3 (eds Corcoran, J. W. & Hahn, F. E.) 79–100 (Springer, Berlin, 1975).
Luck, G. & Arcamone, F. Nucleic Acids Res. 4, 2655–2670 (1977).
Wartell, R. M. & Wells, J. biol. Chem. 249, 6719–6731 (1974).
Krey, A. K. & Hahn, F. E. FEBS Lett. 10, 175–178 (1970).
Kolchinski, A. M. & Mirzabekhov, A. D. Molec. Biol. (USSR) 9, 14–20 (1975).
Luck, G. & Zimmer, Ch. Nucleic Acids Res. 1, 503–530 (1974).
Reinert, K. E. J. molec. Biol. 72, 593–607 (1972).
Nosikov, V. & Jain, B. Nucleic Acids Res. 4, 2263–2273 (1977).
Hogan, M., Dattagupta, N. & Crothers, D. M. Proc. natn. Acad. Sci. U.S.A. 75, 195–199 (1978).
Hogan, M., Dattagupta, N. & Crothers, D. M. Biochemistry 18, 280–288 (1979).
O'Konski, C. T., Yoshioka, K. & Orttung, W. H. J. phys. Chem. 63, 1558–1565 (1959).
Allen, F. S. & Van Holde, K. E. Biopolymers 10, 865–881 (1971).
Lehrman, E. A. & Crothers, D. M. Nucleic Acids Res. 4, 1381–1392 (1977).
Seising, E., Wells, R. D., Early, T. A. & Kearns, D. R. Nature 275, 249–250 (1978).
Scatchard, G. Ann. N.Y. Acad. Sci. 51, 660–672 (1949).
Eshaghpour, H. & Crothers, D. M. Nucleic Acids Res. 5, 13–21 (1978).
Klevan, L. & Crothers, D. M. Nucleic Acids Res. 4, 4077–4090 (1977).
Broersma, S. J. chem. Phys. 32, 1626–1631 (1960).
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Hogan, M., Dattagupta, N. & Crothers, D. Transmission of allosteric effects in DNA. Nature 278, 521–524 (1979). https://doi.org/10.1038/278521a0
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DOI: https://doi.org/10.1038/278521a0
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