Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei

Abstract

Denaturing gel electrophoresis of chick oviduct nuclear RNA reveals multiple species of RNA that are 1.5–5 times larger than ovomucoid mRNA. By analogy with ovalbumin RNA processing, these data suggest that ovomucoid mRNA is derived from a primary transcript that contains intervening sequences.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. O'Malley, B. W., McGuire, W. L., Kohler, P. O. & Korenman, S. G. Recent Prog. Horm. Res. 25, 105–160 (1969).

    CAS  PubMed  Google Scholar 

  2. Chan, L., Means, A. R. & O'Malley, B. W. Proc. natn. Acad. Sci. U.S.A. 70, 1870–1874 (1973).

    Article  ADS  CAS  Google Scholar 

  3. Rhoads, R. E., McKnight, G. S. & Schimke, R. T. J. biol. Chem. 248, 2031–2039 (1973).

    CAS  PubMed  Google Scholar 

  4. Palmiter, R. D. J. biol. Chem. 248, 8260–8270 (1973).

    CAS  PubMed  Google Scholar 

  5. Cox, R. F., Haines, M. E. & Emtage, J. S. Eur. J. Biochem. 47, 225–236 (1974).

    Article  Google Scholar 

  6. Harris, S. E., Rosen, J. M., Means, A. R. & O'Malley, B. W. Biochemistry 14, 2072–2081 (1975).

    Article  CAS  Google Scholar 

  7. Roop, D. R., Nordstrom, J. L., Tsai, S. Y., Tsai, M.-J. & O'Malley, B. W. Cell 15, 671–685 (1978).

    Article  CAS  Google Scholar 

  8. Hynes, N. E., Groner, B., Sippel, A. E., Nguyen-Huu, M. C. & Schütz, G. Cell 11, 923–932 (1977).

    Article  CAS  Google Scholar 

  9. Tsai, S. Y. et al. Biochemistry 17, 5773–5780 (1978).

    Article  CAS  Google Scholar 

  10. McKnight, G. S. Cell 14, 403–413 (1978).

    Article  CAS  Google Scholar 

  11. Tsai, M.-J., Tsai, S. Y. & O'Malley, B. W. Science (in the press).

  12. Swaneck, G. E., Nordstrom, J. L., Kreuzaler, F., Tsai, M.-J. & O'Malley, B. W. Proc. natn. Acad. Sci. U.S.A. (in the press).

  13. Dugaiczyk, A. et al. Nature 274, 328–333 (1978).

    Article  ADS  CAS  Google Scholar 

  14. Mandel, J. L. et al. Cell 14, 641–653 (1978).

    Article  CAS  Google Scholar 

  15. Stein, J. P., Catterall, J. F., Woo, S. L. C., Means, A. R. & O'Malley, B. W. Biochemistry 17, 5763–5772 (1978).

    Article  CAS  Google Scholar 

  16. Alwine, J. C., Kemp, D. J. & Stark, G. R. Proc. natn. Acad. Sci. U.S.A. 74, 5350–5354 (1977).

    Article  ADS  CAS  Google Scholar 

  17. Lehrach, H., Diamond, D., Wozney, J. M. & Boedtker, H. Biochemistry 16, 4743–4751 (1977).

    Article  CAS  Google Scholar 

  18. Bailey, J. M. & Davidson, N. Analyt. Biochem. 70, 75–85 (1976).

    Article  CAS  Google Scholar 

  19. Catterall, J. et al. Nature 278, 323–327 (1979).

    Article  ADS  CAS  Google Scholar 

  20. Curtis, P. J. & Weissman, C. J. molec. Biol. 106, 1061–1075 (1976).

    Article  CAS  Google Scholar 

  21. Ross, J. J. molec. Biol. 106, 403–420 (1976).

    Article  CAS  Google Scholar 

  22. Bastos, R. N. & Aviv, H. Cell 11, 641–650 (1977).

    Article  CAS  Google Scholar 

  23. Kwan, S.-P., Wood, T. S. & Lingrel, J. B. Proc. natn. Acad. Sci. U.S.A. 74, 178–182 (1977).

    Article  ADS  CAS  Google Scholar 

  24. Ross, J. & Knecht, D. A. J. molec. Biol. 119, 1–20 (1978).

    Article  CAS  Google Scholar 

  25. Kinniburgh, A. J., Mertz, J. E. & Ross, J. Cell 14, 681–693 (1978).

    Article  CAS  Google Scholar 

  26. Tilghman, S. M., Curtis, P. J., Tiemeier, D. C., Leder, P. & Weissman, C. Proc. natn. Acad. Sci. U.S.A. 75, 1309–1313 (1978).

    Article  ADS  CAS  Google Scholar 

  27. Lai, E. C. et al. (in preparation).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Nordstrom, J., Roop, D., Tsai, MJ. et al. Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei. Nature 278, 328–331 (1979). https://doi.org/10.1038/278328a0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/278328a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing