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Steroid-induced meiotic division in Xenopus laevis oocytes: surface and calcium

Nature volume 275, pages 593–598 (1978)Cite this article

Abstract

Progesterone reinitiates meiotic maturation in Xenopus laevis oocytes. Evidence is reported which indicates that the steroid acts at the level of the cell surface and suggests that an induced change of Ca2+ distribution triggers in turn a cascade of cytoplasmic events including protein synthesis and germinal vesicle (nucleus) breakdown. These novel features of steroid hormone action in amphibian oocytes are discussed in relation to presently accepted views of the mechanism of action of steroid hormones in somatic cells.

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Authors and Affiliations

  1. Lab. Hormones, INSERM, Faculté de Médecine, Université Paris-Sud, France

    Etienne-Emile Baulieu & François Godeau

  2. Département de Pharmacologie, Ecole de Médecine, Université de Genève, Switzerland

    Michel Schorderet

  3. Station de Zoologie expérimentale, Université de Genéve, Switzerland

    Sabine Schorderet-Slatkine

Authors
  1. Etienne-Emile Baulieu
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  2. François Godeau
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  3. Michel Schorderet
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  4. Sabine Schorderet-Slatkine
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Baulieu, EE., Godeau, F., Schorderet, M. et al. Steroid-induced meiotic division in Xenopus laevis oocytes: surface and calcium. Nature 275, 593–598 (1978). https://doi.org/10.1038/275593a0

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