Abstract
Nonsense mutations derived from 90 different codons in the lacI gene of Escherichia coli have been correlated with the I gene nucleotide sequence. In over 80 cases the specific codon which generates the nonsense mutation can be identified. The sequence shows that 14–16 sites arise through tandem double base changes.
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Miller, J., Coulondre, C. & Farabaugh, P. Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence. Nature 274, 770–775 (1978). https://doi.org/10.1038/274770a0
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DOI: https://doi.org/10.1038/274770a0
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