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A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cells

Nature volume 274, pages 445–449 (1978)Cite this article

Abstract

During the acquisition of aggregation competence a new antigen appears on the surface of Dictyostelium cells. Univalent antibody fragments (Fab) against this antigen render the cells unable to form the specific type of cell adhesion which is characteristic of aggregating cells. This membrane constituent has been purified and identified as a concanavalin A-binding glycoprotein present at about 2 × 105 copies per cell.

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Authors and Affiliations

  1. Biozentrum der Universität Basel, Klingelbergstrasse 70, 4056, Basel, Switzerland

    Kurt Müller & Günther Gerisch

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  1. Kurt Müller
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  2. Günther Gerisch
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Müller, K., Gerisch, G. A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cells. Nature 274, 445–449 (1978). https://doi.org/10.1038/274445a0

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