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Membrane leakiness after viral infection and a new approach to the development of antiviral agents

Nature volume 272, pages 694–699 (1978)Cite this article

Abstract

Viral development induces changes in the permeability properties of the plasma membrane of the host cell. Here it is shown that, because of this leakiness, inhibitors of protein synthesis normally impermeable to uninfected cells are able to enter infected cells and thereby specifically inhibit viral protein synthesis.

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Author notes

  1. Luis Carrasco

    Present address: Insto, Bioquimica de Macromoleculas, Centro de Biologia Molecular, Universidad Autónoma de Madrid, Facultad de Ciencias, Canto Blanco, Madrid, 34, Spain

Authors and Affiliations

  1. Translation Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, WC2, UK

    Luis Carrasco

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  1. Luis Carrasco
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Carrasco, L. Membrane leakiness after viral infection and a new approach to the development of antiviral agents. Nature 272, 694–699 (1978). https://doi.org/10.1038/272694a0

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