Letter | Published:

Circulating immune complexes in infants fed on cow's milk

Nature volume 272, page 632 (13 April 1978) | Download Citation

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Abstract

CIRCULATING antigen–antibody (AgAb) complexes are capable of damaging various tissues, for example, renal glomeruli, vessels and joints1. In addition, immune complexes (IC) can interfere with cellular immunity and, to some extent, decrease the immune response2–4. We report here that all infants fed on cow's milk have circulating complexes containing bovine proteins as antigens and IgG antibodies of maternal origin. These data raise questions as to the possible involvement of such complexes in various disorders, the intestinal resorption of macromolecules, and the development of antibodies against food antigens.

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Affiliations

  1. Unit of Experimental Medicine, International Institute of Cellular and Molecular Pathology, Université Catholique de Louvain, 75, avenue Hippocrate, B-1200 Brussels, Belgium

    • M. DELIRE
    • , C. L. CAMBIASO
    •  & P. L. MASSON

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DOI

https://doi.org/10.1038/272632a0

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