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Gene K, a new overlapping gene in bacteriophage G4

Abstract

A third overlapping gene in the isometric bacteriophages has been identified by nucleotide sequence analysis of the G4 genome and by isolation and microsequence analysis of the new protein. Five nucleotides are used in all three translational reading frames of the DNA.

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References

  1. Godson, G. N. Virology 58, 272–289 (1974).

    Article  CAS  PubMed  Google Scholar 

  2. Sanger, F. et al. Nature 265, 687–695 (1977).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Smith, M. et al. Nature 265, 702–705 (1977).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Barrell, B. G., Air, G. M. & Hutchison, C. A., III Nature 264, 34–41 (1976).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Barrell, B. G. International Review of Biochemistry 17 (ed. Clark, B. F. C.) (University Park Press, Baltimore, in the press).

  6. Shine, J. & Dalgarno, L. Eur. J. Biochem. 57, 221–230 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. Steitz, J. A. & Jakes, K. Proc. natn. Acad. Sci. U.S.A. 72, 4734–4738 (1975).

    Article  ADS  CAS  Google Scholar 

  8. Sanger, F., Nicklen, S. & Coulson, A. R. Proc. natn. Acad. Sci. U.S.A. 74, 5463–5467 (1977).

    Article  ADS  CAS  Google Scholar 

  9. Denhardt, D. T. Comprehensive Virology 7 (in the press).

  10. Air, G. M. J. molec. Biol. 107, 433–443 (1976).

    Article  CAS  PubMed  Google Scholar 

  11. Air, G. M. et al. J. molec. Biol. 107, 445–458 (1976).

    Article  CAS  PubMed  Google Scholar 

  12. Air, G. M., Sanger, F. & Coulson, A. R. J. molec. Biol. 108, 519–533 (1976).

    Article  CAS  PubMed  Google Scholar 

  13. Benbow, R. M., Mayol, R. F., Picchi, J. C. & Sinsheimer, R. L. J. Virol. 10, 99–114 (1972).

    CAS  PubMed  PubMed Central  Google Scholar 

  14. Benbow, R. M., Hutchinson, C. A., III, Fabricant, J. D. & Sinsheimer, R. L. J. Virol. 7, 549–558 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  15. Weisbeek, P. J., Borrias, W. E., Langeveld, S. A., Baas, P. D. & van Arkel, G. A. Proc. natn. Acad. Sci. U.S.A. 74, 2504–2508 (1977).

    Article  ADS  CAS  Google Scholar 

  16. Haugen, D. A., Armes, L. G., Yasunobu, K. T. & Coon, M. J. Biochem. biophys. Res. Commun. 77, 967–973 (1977).

    Article  CAS  PubMed  Google Scholar 

  17. Devillers-Thiery, A., Kindt, T., Scheele, G. & Blobel, G. Proc. natn. Acad. Sci. U.S.A. 72, 5016–5020 (1975).

    Article  ADS  CAS  Google Scholar 

  18. Burstein, Y. & Schechter, I. Proc. natn. Acad. Sci. U.S.A. 74, 716–720 (1977).

    Article  ADS  CAS  Google Scholar 

  19. Birken, S., Smith, D. L., Canfield, R. E. & Boime, I. Biochem. biophys. Res. Commun. 74, 106–112 (1977).

    Article  CAS  PubMed  Google Scholar 

  20. Strauss, A. W., Donohue, A. M., Bennett, C. D., Rodkey, J. A. & Alberts, A. W. Proc. natn. Acad. Sci. U.S.A. 74, 1358–1362 (1977).

    Article  ADS  CAS  Google Scholar 

  21. Sanger, F. & Coulson, A. R. J. molec. Biol. 94, 441–448 (1975).

    Article  CAS  PubMed  Google Scholar 

  22. Laemmli, U. K. Nature, 227, 680–685 (1970).

    Article  ADS  CAS  PubMed  Google Scholar 

  23. Walker, J. E., Shaw, D. C., Northrop, F. D. & Horsnell, T. Solid Phase Methods in Protein Sequence Analysis (ed. Previero, A. & Coletti-Previero, M. A.) 277–285 (North-Holland, Amsterdam, 1978).

    Google Scholar 

  24. Capra, J. D., Wilde, C. E. & Klapper, D. G. Solid Phase Methods in Protein Sequence Analysis (ed.Previero, A. & Coletti-Previero, M. A.) 69–80 (North-Holland, Amsterdam, 1978).

    Google Scholar 

  25. Mendez, E. & Lai, C. Y. Analyt. Biochem. 68, 47–53 (1975).

    Article  CAS  PubMed  Google Scholar 

  26. McKean, D. J., Peters, E. H., Waldby, J. I. & Smithies, O. Biochemistry 13, 3048–3051 (1974).

    Article  CAS  PubMed  Google Scholar 

  27. Biochem. J., 113, 1–4 (1969).

  28. Linney, E. & Hayashi, M. Nature new Biol. 245, 6–8 (1973).

    Article  CAS  PubMed  Google Scholar 

  29. Freymeyer, D. K. et al. Biochemistry 16, 4550–4556 (1977).

    Article  CAS  PubMed  Google Scholar 

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Shaw, D., Walker, J., Northrop, F. et al. Gene K, a new overlapping gene in bacteriophage G4. Nature 272, 510–515 (1978). https://doi.org/10.1038/272510a0

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