Abstract
FOOT-SHOCK induced stress promotes a five to sixfold increase in β-endorphin plasma levels. Similar increases were also found for ACTH plasma levels. In the hypothalamus, foot-shock induced stress promotes a decrease of β-endorphin assayed by radioimmunoassays. These data suggest that physiological increases in plasma β-endorphin levels induced by stress do not result in elevated levels of brain β-endorphin.
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ROSSIER, J., FRENCH, E., RIVIER, C. et al. Foot-shock induced stress increases β-endorphin levels in blood but not brain. Nature 270, 618–620 (1977). https://doi.org/10.1038/270618a0
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DOI: https://doi.org/10.1038/270618a0
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