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Evolution of ageing


An evolutionary view of ageing suggests that mortality may be due to an energy-saving strategy of reduced error regulation in somatic cells. This supports Orgel's ‘error catastrophe’ hypothesis and offers a new basis for the study of normal and abnormal ageing syndromes and of apparently immortal transformed cell lines.

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Kirkwood, T. Evolution of ageing. Nature 270, 301–304 (1977).

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