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Possible regulatory function of acetylcholine receptor in maintenance of retinotectal synapses

Nature volume 269, pages 218–222 (1977)Cite this article

Abstract

α-Neurotoxins bind to cholinergic receptor, block transmission, and induce sprouting of retinal terminals in the toad tectum. New connections retain an orderliness that suggests a selective affinity between presynaptic terminals. The results suggest that postsynaptic cells exert a control, associated with receptors, on the growth of presynaptic terminals and on the maintenance of their synaptic connections.

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Authors and Affiliations

  1. Vanderbilt University Medical School, Nashville, Tennessee, 37232

    John A. Freeman

  2. National Institute for Medical Research, London, NW7, UK

    John A. Freeman

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  1. John A. Freeman
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Freeman, J. Possible regulatory function of acetylcholine receptor in maintenance of retinotectal synapses. Nature 269, 218–222 (1977). https://doi.org/10.1038/269218a0

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