Scientific Correspondence | Published:

Receptor that leaves a sour taste in the mouth

Naturevolume 395pages555556 (1998) | Download Citation

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Abstract

The ability to detect taste stimuli results from the activation of taste receptors located in taste-bud cells. There are several gustatory transduction mechanisms, involving membrane receptors, guanine-nucleotide-binding proteins (G proteins), second messengers and ion channels1, but genes encoding taste receptors have not yet been identified. Here we identify a complementary DNA that encodes a receptor for sour tastes.

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Affiliations

  1. Department of Anatomy II, Nagoya City University Medical School, 1 Kawasumi, Mizuho-cho, Nagoya, 467–8601, Mizuho-ku, Japan

    • Shinya Ugawa
    • , Wei Guo
    • , Yoshitsugu Saishin
    •  & Shoichi Shimada
  2. Department of Anatomy and Neuroscience, Osaka University Medical School, 2-2 Yamadaoka, Suita, 565–0871, Osaka, Japan

    • Shinya Ugawa
    • , Yuki Minami
    • , Wei Guo
    • , Yoshitsugu Saishin
    • , Koichi Takatsuji
    •  & Masaya Tohyama
  3. Department of Behavioural Physiology, Faculty of Human Sciences, Osaka University, 1-2 Yamadaoka, Suita, 565-0871, Osaka, Japan

    • Takashi Yamamoto

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https://doi.org/10.1038/26882

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