Abstract
EFFORTS directed towards the enumeration of effector cells involved in the cell-mediated immune response have so far met with little success. One of the principal reasons for this failure is the current ignorance of relationships between killer, lymphokine producer and suppressor T cells, all of which have effector functions. To date, attempts at quantification have focused principally on cytolytically active (killer) T cells largely because in vitro assays using target cells labelled with radioisotopes afford sensitive and reproducible measurement of their function1.
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References
Brunner, K. T., Mauel, J., Cerottini, J.-C., and Chapuis, B., Immunology, 14, 181–196 (1968).
Zagury, D., Bernard, J., Thierness, N., Feldman, M., and Berke, G., Eur. J. Immun., 5, 818–822 (1975).
Martz, E., Transplantation, 21, 5–11 (1976).
Plaut, M., Bubbers, J. E., and Henney, C. S., J. Immun., 116, 150–155 (1976).
Bubbers, J. E., and Henney, C. S., J. Immun., 115, 145–149 (1975).
Henney, C. S., J. Immun., 107, 1558–1566 (1971).
Cerottini, J.-C., Nordin, A. A., and Brunner, K. T., Nature, 228, 1308–1309 (1970).
Berke, G., Gabison, D., and Feldman, M., Eur. J. Immun., 5, 813–818 (1975).
MacDonald, H. R., Eur. J. Immun., 5, 251–254 (1975).
Wilson, D., J. exp. Med., 122, 143–166 (1975).
Martz, E., J. Immun., 115, 261–267 (1975).
Mage, M. G., and McHugh, L. L., J. Immun., 115, 911–913 (1975).
Kamat, R., and Henney, C. S., J. Immun., 115, 1592–1598 (1975).
Cerottini, J. -C., Engers, H. D., MacDonald, H. R., and Brunner, K. T., J. exp. Med., 140, 718–730 (1974).
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THORN, R., HENNEY, C. Enumeration of specific cytotoxic T cells. Nature 262, 75–77 (1976). https://doi.org/10.1038/262075a0
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DOI: https://doi.org/10.1038/262075a0
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