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Evidence for post-transcriptional selection of viral mRNA in cells transformed by human adenovirus 12

Abstract

CONTROL of gene expression occurs mainly at the transcriptional level in prokaryotic cells1. In eukaryotic cells, the sites of transcription and translation are physically separated by the nuclear membrane, giving rise to the possibility of regulation by post-transcriptional mechanisms. Control could be exercised at several stages of mRNA biogenesis: methylation, polyadenylation, cleavage, or transport across the nuclear membrane2,3.

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GREEN, M., GREEN, M. & MACKEY, J. Evidence for post-transcriptional selection of viral mRNA in cells transformed by human adenovirus 12. Nature 261, 340–342 (1976). https://doi.org/10.1038/261340a0

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