Abstract
THE X-linked testicular feminisation mutant (Tfm) in the mouse produces chromosomally male animals, XTfm/Y, with small testes but no other internal reproductive organs, and with female external genitalia1. This condition results fromfailure of target tissues to respond to testosterone, so that all characters of maleness that are testosterone-dependent are absent in males2–4.
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BENNETT, D., BOYSE, E., LYON, M. et al. Expression of H–Y (male) antigen in phenotypically female Tfm/Y mice. Nature 257, 236–238 (1975). https://doi.org/10.1038/257236a0
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DOI: https://doi.org/10.1038/257236a0
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