Letter | Published:

Permeability of solutes through biological membranes measured by a desorption technique

Naturevolume 257pages225227 (1975) | Download Citation

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Abstract

THE influence of molecular structure of a solute on its permeation through biological membranes has been evaluated by various methods1–4. For permeation of a solute across a membrane of thickness, h, the permeability coefficient, P, can be expressed in terms of the membrane–solution partition coefficient (Km) and the diffusion coefficient in the membrane (D): P=KmD/h (1)

References

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Affiliations

  1. Department of Pharmacy, University of Sydney, New South Wales, 2006, Australia

    • M. S. ROBERTS
    • , E. J. TRIGGS
    •  & R. A. ANDERSON

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https://doi.org/10.1038/257225a0

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