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Three-dimensional model of purple membrane obtained by electron microscopy

Nature volume 257, pages 2832 (04 September 1975) | Download Citation

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Abstract

A 7-Å resolution map of the purple membrane has been obtained by electron microscopy of tilted, unstained specimens. The protein in the membrane contains seven, closely packed, α-helical segments which extend roughly perpendicular to the plane of the membrane for most of its width. Lipid bilayer regions fill the spaces between the protein molecules.

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References

  1. 1.

    , and , J. Cell Biol., 38, 337–357 (1968).

  2. 2.

    , and , Proc. natn. Acad. Sci. U.S.A., 70, 2853–2857 (1973).

  3. 3.

    , and , Nature new Biol., 233, 149–152 (1971).

  4. 4.

    , and , Nature new Biol., 233, 152–155 (1971).

  5. 5.

    , and , J. molec. Biol., 94, 425–440 (1975).

  6. 6.

    , and , Nature, 217, 130–134 (1968).

  7. 7.

    , J. molec. Biol., 93, 123–138 (1975).

  8. 8.

    , in Physical Aspects of Electron Microscopy and Microbeam Analysis (edit. by Siegel, B., and Beaman, D. R.), 205 (Wiley, New York, 1975).

  9. 9.

    , J. molec. Biol., 93, 139–158 (1975).

  10. 10.

    , Acta Cryst., 6, 689–697 (1953).

  11. 11.

    , and , Science, 175, 720–731 (1972).

  12. 12.

    , Science, 181, 622–629 (1973).

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Affiliations

  1. MRC Laboratory of Molecular biology, Hills Road, Cambridge CB2 2QH, UK

    • R. Henderson
    •  & P. N. T. Unwin

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DOI

https://doi.org/10.1038/257028a0

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