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Influence of haemoglobin type on the induced ovulation rate in sheep

Naturevolume 256pages738739 (1975) | Download Citation



HARRIS and Warren1 first reported haemoglobin (Hb) polymorphism in sheep; they separated a fast moving Hb A, and a slower moving Hb B, which were controlled by a single pair of alleles yielding three phenotypes—AA, BB and AB (ref 2). Several investigators have subsequently reported on the influence of Hb type on the reproductive performance of sheep. Evans and Turner3 found that Merino ewes of Hb types BB and AB were more fertile and had a greater proportion of multiple births than AA ewes; subsequent investigations have confirmed this observation4. In a study of Australian Merino ewes grazing oestrogenic clover pastures Obst et al.5 reported that AA and BB ewes were significantly more fertile than BB animals, suggesting that the A gene is associated with some factor which protects against the deleterious effects of plant oestrogens. We report observations in Indian Bikaneri ewes and suggest an association between Hb type and the ovarian response to exogenous gonadotrophins.

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  1. 1

    Harris, H., and Warren, F. L., Biochem. J., 60, 29 (1955).

  2. 2

    Evans, J. V., King, J. W. B., Cohen, B. L., Harris, H., and Warren, F. L., Nature, 178, 849 (1956).

  3. 3

    Evans, J. V., and Turner, H. N., Nature, 207, 1396 (1965).

  4. 4

    Seth, O. N., Curr. Sci., 37, 231 (1968).

  5. 5

    Obst, J. M., Seamark, R. F., and McGowan, C. J., Nature, 232, 497 (1971).

  6. 6

    Fowler, R. E., and Edwards, R. G., J. Endocr., 15, 374 (1957).

  7. 7

    Nalbandov, N. V., in Reproductive Physiology, second ed., 76 (Freeman, W. H., San Francisco).

  8. 8

    McLaren, A., J. Endocr., 25, 137 (1962).

  9. 9

    Land, R. B., and Falconer, D. S., Genet. Res., 13, 25 (1969).

  10. 10

    Bindon, B. M., and Pennycuik, P. R., J. Reprod. Fert., 36, 221 (1974).

  11. 11

    Bindon, B. M., Chang, T. S., and Turner, H. N., Aust. J. Agric. Res., 22, 809 (1971).

  12. 12

    Lamond, D. R., and Emmens, C. W., J. Endocr., 18, 251 (1959).

  13. 13

    Lamond, D. R., and Bindon, B. M., Nature, 209, 512 (1966).

  14. 14

    Thimonier, J., and Pelletier, J., Annls Biol. anim. Biochim. Biophys., 11, 559 (1971).

  15. 15

    Wallace, L. R., J. agric. Sci., Camb., 45, 60 (1955).

  16. 16

    Gordon, I., J. agric. Sci., Camb., 50, 123 (1958).

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  1. Department of Physiology and Biochemistry, Veterinary College, PO Mathura, U.P., India

    • H. C. PANT
    •  & M. D. PANDEY


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