Abstract
THE fidelity of the transfer of the genetic information at the translational level depends largely on the accuracy with which each transfer RNA (tRNA) is aminoacylated by its cognate synthetase. The search for the common sites on tRNA which the enzyme recognises has resulted so far in a rather confusing picture. Practically all parts of the tRNA molecule have been implicated as the possible recognition site(s)1,2.
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KIM, SH. Symmetry recognition hypothesis model for tRNA binding to aminoacyl-tRNA synthetase. Nature 256, 679–681 (1975). https://doi.org/10.1038/256679a0
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DOI: https://doi.org/10.1038/256679a0
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