Letter | Published:

Oestrogen-responsive human breast cancer in long term tissue culture

Naturevolume 256pages592593 (1975) | Download Citation



STUDIES of steroid hormone dependence of human breast cancer have been hampered by a lack of a suitable in vitro model system which can reproduce the responses of human breast cancer observed in vivo. We now report the characterisation of several human breast cancer cell lines, at least one of which shows marked dependence on oestrogens for growth. This oestrogen dependence seems to be similar in a variety of ways to that observed clinically in vivo.

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  1. Medical Breast Cancer Section, Medicine Branch, National Cancer Institute, Bethesda, Maryland, 20014

    •  & GAIL BOLAN


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