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E. coli membrane lipid alteration affecting T4 capsid morphogenesis

Naturevolume 256pages379383 (1975) | Download Citation

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Abstract

An Escherichia coli mutant, hd B3-1, cold sensitive for T4+ capsid assembly is described. The hd B3-1 character seems to be caused by altered lipid components of the bacterial inner membrane. The genetic locus for the hd B3-1 phenotype is designated fat A and is closely linked to proline.

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References

  1. 1

    Simon, L. D., Proc. natn. Acad. Sci. U.S.A., 69, 907–911 (1972).

  2. 2

    Takano, T., and Kakefuda, T., Nature new Biol., 239, 34–37 (1972).

  3. 3

    Coppo, A., Manzi, A., Pulitzer, J. F., and Takahashi, H., J. molec. Biol., 76, 61–87 (1973).

  4. 4

    Georgopolous, C. P., Hendrix, R. W., Kaiser, A. D., and Wood, W. B., Nature new Biol., 239, 38–41 (1972).

  5. 5

    Laemmli, U. K., Beguin, F., and Gujer-Kellenberger, G., J. molec. Biol., 47, 69–85 (1970).

  6. 6

    Osborn, M. J., Gander, J. E., Parisi, E., and Carson, J., J. biol. Chem., 247, 3962–3972 (1972).

  7. 7

    Heinz, H., and Sturdervant, J., J. biol. Chem., 247, 6071–6075 (1972).

  8. 8

    Shimshick, E. J., and McConnell, H. M., Biochemistry, 12, 2351–2360 (1973).

  9. 9

    Linden, C. D., Wright, K. L., McConnell, H. M., and Fox, C. F., Proc. natn. Acad. Sci. U.S.A., 70, 2271–2275 (1973).

  10. 10

    Sackmann, E., Trauble, H., Galla, H. J., and Overath, P., Biochemistry, 12, 5360–5369 (1973).

  11. 11

    Bligh, E. J., and Dyer, W. J., Can. J. biochem. Physiol., 37, 911–917 (1959).

  12. 12

    Dittmer, J. C., and Lester, R. L., J. lipid Res., 5, 126–127 (1964).

  13. 13

    Cronan, Jr., J. E., and Vagelos, P. R., Biochim. biophys. Acta, 265, 25–60 (1972).

  14. 14

    Ackman, R. G., in Methods in Enzymology, 14, (edit. by Lowenstein, J. M.), 329–381 (Academic, New York, 1969).

  15. 15

    Kanemasa, Y., Akamatsu, Y., and Nojima, S., Biochim. biophys. Acta, 144, 382–390 (1967).

  16. 16

    Weintraub, S. B., and Frankel, F. R., J. molec. Biol., 70, 589–615 (1972).

  17. 17

    Merlie, J. P., Biochimie, 56, 717–728 (1974).

  18. 18

    Grisham, C., and Barnett, R., Biochemistry, 12, 2635–2637 (1973).

  19. 19

    Dittmer, J. C., and Wells, M. A., in Methods in Enzymology, 14, (edit. by Lowenstein, J. M.), 482–530 (Academic, New York, 1969).

  20. 20

    Waggoner, A., Kingzett, T., Rottschaefer, S., and Griffith, O., Chem. phys. Lipids, 3, 245 (1969).

  21. 21

    Klein, K., Steinberg, R., Fiethen, B., and Overath, P., Eur. J. Biochem., 19, 442 (1971).

  22. 22

    Laemmli, U. K., Nature, 227, 680 (1970).

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Author information

Author notes

    • Dale Snover

    Present address: The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania, 17033

    • Charles Grisham

    Present address: Department of Chemistry, University of Virginia, Charlottesville, Virginia, 22901

Affiliations

  1. The Institute for Cancer Research, The Fox Chase Center for Cancer and Medical Sciences, Philadelphia, Pennsylvania, 19111

    • Lee D. Simon
    • , Thomas J. M. McLaughlin
    • , Dale Snover
    • , Jonathan Ou
    • , Charles Grisham
    •  & Marilyn Loeb

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https://doi.org/10.1038/256379a0

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